Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2010-3-2
pubmed:abstractText
Dendritic cells (DCs) have been extensively studied in mice lymphoid organs, but less is known about the origin and the mechanisms that regulate DC development and function in non-lymphoid tissues. Here, we discuss recent evidence establishing the contribution of the DC-restricted lineage to the non-lymphoid tissue DC pool and discuss the mechanisms that control the homeostasis of non-lymphoid tissue DCs. We also review recent results underlining the functional specialization of tissue DCs and discuss the potential implications of these findings in tissue immunity and in the development of novel vaccine strategies.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1600-065X
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
234
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
55-75
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Origin and functional heterogeneity of non-lymphoid tissue dendritic cells in mice.
pubmed:affiliation
Department of Gene and Cell Medicine and Mount Sinai School of Medicine, New York, NY, USA.
pubmed:publicationType
Journal Article, Review, Research Support, N.I.H., Extramural