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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2010-1-26
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pubmed:abstractText |
Human lung cancer patients exhibit different KRAS mutations depending on smoking status. In a mouse model of human cancer, A/J and BALB/cBy mice treated with the tobacco carcinogen, 3-methylcholanthrene (MCA), followed by butylated hydroxytoluene (BHT)-elicited chronic inflammation develop a high multiplicity of lung tumors.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/20101149-10545420,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20101149-11293324,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20101149-11390008,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20101149-12509763,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20101149-15059877,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20101149-17882278,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20101149-18030469,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20101149-18299280,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20101149-18794081,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20101149-18932251,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20101149-2364382,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20101149-2654935,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20101149-9659579,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20101149-9696043
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1556-1380
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
254-7
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pubmed:dateRevised |
2011-9-26
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pubmed:meshHeading |
pubmed-meshheading:20101149-Adenocarcinoma,
pubmed-meshheading:20101149-Animals,
pubmed-meshheading:20101149-Butylated Hydroxytoluene,
pubmed-meshheading:20101149-Codon,
pubmed-meshheading:20101149-Humans,
pubmed-meshheading:20101149-Lung Neoplasms,
pubmed-meshheading:20101149-Methylcholanthrene,
pubmed-meshheading:20101149-Mice,
pubmed-meshheading:20101149-Mice, Inbred Strains,
pubmed-meshheading:20101149-Mutation,
pubmed-meshheading:20101149-Polymerase Chain Reaction,
pubmed-meshheading:20101149-Proto-Oncogene Proteins,
pubmed-meshheading:20101149-Proto-Oncogene Proteins p21(ras),
pubmed-meshheading:20101149-Smoking,
pubmed-meshheading:20101149-ras Proteins
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pubmed:year |
2010
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pubmed:articleTitle |
The Kras mutational spectra of chemically induced lung tumors in different inbred mice mimics the spectra of KRAS mutations in adenocarcinomas in smokers versus nonsmokers.
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pubmed:affiliation |
Department of Pharmaceutical Sciences, University of Colorado Denver, Aurora, Colorado 80045, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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