rdf:type |
|
lifeskim:mentions |
umls-concept:C0005528,
umls-concept:C0008783,
umls-concept:C0021467,
umls-concept:C0021469,
umls-concept:C0022702,
umls-concept:C0086418,
umls-concept:C0205198,
umls-concept:C0205245,
umls-concept:C0596902,
umls-concept:C0682323,
umls-concept:C0874159,
umls-concept:C1521970,
umls-concept:C1979963,
umls-concept:C2003903
|
pubmed:issue |
3
|
pubmed:dateCreated |
2010-1-13
|
pubmed:abstractText |
Human multidrug and toxin extrusion protein 1 (hMATE1) and hMATE2-K are organic cation/H+ antiporters that have recently been identified and suggested to be involved in the renal brush border secretion of various organic cations. Information about functional characteristics of them has been accumulating, but still insufficient to fully understand their functions and respective roles. The present study was conducted to help clarify them.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antiporters,
http://linkedlifedata.com/resource/pubmed/chemical/Cimetidine,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Complementary,
http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/MATE1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/MATE1 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/MATE2-K protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Organic Cation Transport Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Tetraethylammonium
|
pubmed:status |
MEDLINE
|
pubmed:issn |
1482-1826
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
12
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
388-96
|
pubmed:meshHeading |
pubmed-meshheading:20067714-Animals,
pubmed-meshheading:20067714-Antiporters,
pubmed-meshheading:20067714-Cell Line, Tumor,
pubmed-meshheading:20067714-Cimetidine,
pubmed-meshheading:20067714-DNA, Complementary,
pubmed-meshheading:20067714-Enzyme Inhibitors,
pubmed-meshheading:20067714-Humans,
pubmed-meshheading:20067714-Kidney,
pubmed-meshheading:20067714-Kinetics,
pubmed-meshheading:20067714-Organic Cation Transport Proteins,
pubmed-meshheading:20067714-Rats,
pubmed-meshheading:20067714-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:20067714-Species Specificity,
pubmed-meshheading:20067714-Tetraethylammonium,
pubmed-meshheading:20067714-Transfection
|
pubmed:year |
2009
|
pubmed:articleTitle |
Functional characteristics of two human MATE transporters: kinetics of cimetidine transport and profiles of inhibition by various compounds.
|
pubmed:affiliation |
Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|