rdf:type |
|
lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0023434,
umls-concept:C0087111,
umls-concept:C0167627,
umls-concept:C0185117,
umls-concept:C0441471,
umls-concept:C0443146,
umls-concept:C0871261,
umls-concept:C1268902,
umls-concept:C1444748,
umls-concept:C1533691,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C1707520,
umls-concept:C2911684,
umls-concept:C2911692
|
pubmed:issue |
3
|
pubmed:dateCreated |
2010-2-22
|
pubmed:abstractText |
Despite a fludarabine-based treatment is the first choice of therapy in chronic lymphocytic leukemia (CLL), not all patients achieve a partial or complete response and some of them develop autoimmune manifestations. The aim of this study was to evaluate the influence of CD154 on these adverse effects because CD154 is involved in both B-cell survival and autoimmunity.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
1873-2399
|
pubmed:author |
|
pubmed:copyrightInfo |
Copyright 2010 ISEH - Society for Hematology and Stem Cells. Published by Elsevier Inc. All rights reserved.
|
pubmed:issnType |
Electronic
|
pubmed:volume |
38
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
165-73
|
pubmed:meshHeading |
pubmed-meshheading:20026377-Aged,
pubmed-meshheading:20026377-Aged, 80 and over,
pubmed-meshheading:20026377-Antineoplastic Agents,
pubmed-meshheading:20026377-Autoimmunity,
pubmed-meshheading:20026377-CD40 Ligand,
pubmed-meshheading:20026377-Cells, Cultured,
pubmed-meshheading:20026377-Cladribine,
pubmed-meshheading:20026377-Female,
pubmed-meshheading:20026377-Flow Cytometry,
pubmed-meshheading:20026377-Humans,
pubmed-meshheading:20026377-Immunophenotyping,
pubmed-meshheading:20026377-Leukemia, Lymphocytic, Chronic, B-Cell,
pubmed-meshheading:20026377-Male,
pubmed-meshheading:20026377-Middle Aged,
pubmed-meshheading:20026377-Outcome Assessment (Health Care),
pubmed-meshheading:20026377-Prognosis,
pubmed-meshheading:20026377-Vidarabine
|
pubmed:year |
2010
|
pubmed:articleTitle |
CD154 expression triggered by purine analogues in vitro: Correlation with treatment response and autoimmune events in chronic lymphocytic leukemia.
|
pubmed:affiliation |
Servicio de Medicina Interna, Hospital Universitario Puerta de Hierro Majadahonda, Universidad Autónoma de Madrid, Majadahonda, Madrid, Spain. mjcitores@telefonica.net
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|