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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2010-2-16
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pubmed:abstractText |
We investigated the mechanism responsible for imatinib (IM) resistance in Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph(+) ALL) cell lines.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Ephrin-B2,
http://linkedlifedata.com/resource/pubmed/chemical/Fusion Proteins, bcr-abl,
http://linkedlifedata.com/resource/pubmed/chemical/Neoplasm Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Piperazines,
http://linkedlifedata.com/resource/pubmed/chemical/Protein Kinase Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Pyrimidines,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Small Interfering,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, EphB4,
http://linkedlifedata.com/resource/pubmed/chemical/imatinib,
http://linkedlifedata.com/resource/pubmed/chemical/ras Proteins
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1600-0609
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pubmed:author |
pubmed-author:AbeAkihiroA,
pubmed-author:EmiNobuhikoN,
pubmed-author:HayakawaFumihikoF,
pubmed-author:ImagamaShizukaS,
pubmed-author:ItoYoshieY,
pubmed-author:KatsumiAkiraA,
pubmed-author:KiyoiHitoshiH,
pubmed-author:MinamiYosukeY,
pubmed-author:NaoeTomokiT,
pubmed-author:NomuraYukaY,
pubmed-author:SuzukiMomokoM,
pubmed-author:TanizakiRyoheiR,
pubmed-author:YamamotoKazuhitoK
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pubmed:issnType |
Electronic
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pubmed:volume |
84
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
229-38
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pubmed:meshHeading |
pubmed-meshheading:20002159-Cell Line, Tumor,
pubmed-meshheading:20002159-Drug Resistance, Neoplasm,
pubmed-meshheading:20002159-Enzyme Activation,
pubmed-meshheading:20002159-Enzyme Induction,
pubmed-meshheading:20002159-Ephrin-B2,
pubmed-meshheading:20002159-Female,
pubmed-meshheading:20002159-Fusion Proteins, bcr-abl,
pubmed-meshheading:20002159-Humans,
pubmed-meshheading:20002159-MAP Kinase Signaling System,
pubmed-meshheading:20002159-Middle Aged,
pubmed-meshheading:20002159-Neoplasm Proteins,
pubmed-meshheading:20002159-Phosphorylation,
pubmed-meshheading:20002159-Piperazines,
pubmed-meshheading:20002159-Precursor Cell Lymphoblastic Leukemia-Lymphoma,
pubmed-meshheading:20002159-Protein Kinase Inhibitors,
pubmed-meshheading:20002159-Protein Processing, Post-Translational,
pubmed-meshheading:20002159-Pyrimidines,
pubmed-meshheading:20002159-RNA, Small Interfering,
pubmed-meshheading:20002159-Receptor, EphB4,
pubmed-meshheading:20002159-Recurrence,
pubmed-meshheading:20002159-ras Proteins
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pubmed:year |
2010
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pubmed:articleTitle |
BCR-ABL-independent and RAS / MAPK pathway-dependent form of imatinib resistance in Ph-positive acute lymphoblastic leukemia cell line with activation of EphB4.
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pubmed:affiliation |
Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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