|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0001511,
umls-concept:C0007301,
umls-concept:C0016030,
umls-concept:C0017262,
umls-concept:C0017710,
umls-concept:C0037083,
umls-concept:C0109317,
umls-concept:C0185117,
umls-concept:C0298340,
umls-concept:C0442805,
umls-concept:C0600210,
umls-concept:C0752312,
umls-concept:C1150579,
umls-concept:C1269955,
umls-concept:C1333340,
umls-concept:C1366882,
umls-concept:C1370600,
umls-concept:C1550315,
umls-concept:C1705767,
umls-concept:C1705791,
umls-concept:C1710082,
umls-concept:C2699153,
umls-concept:C2911684
|
|
pubmed:issue |
12
|
|
pubmed:dateCreated |
2009-12-16
|
|
pubmed:abstractText |
In rheumatoid arthritis (RA), integrins mediate cell adhesion, migration, and invasion, and their expression is regulated by cytokines and growth factors. The aim of this study was to investigate whether hormones such as cortisol or other steroids can influence integrin expression and function in the synovial cells of patients with RA.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
0004-3591
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
60
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
3623-32
|
|
pubmed:meshHeading |
pubmed-meshheading:19950288-Aged,
pubmed-meshheading:19950288-Animals,
pubmed-meshheading:19950288-Antibodies, Neutralizing,
pubmed-meshheading:19950288-Cartilage, Articular,
pubmed-meshheading:19950288-Cell Movement,
pubmed-meshheading:19950288-Cells, Cultured,
pubmed-meshheading:19950288-Estradiol,
pubmed-meshheading:19950288-Extracellular Signal-Regulated MAP Kinases,
pubmed-meshheading:19950288-Female,
pubmed-meshheading:19950288-Fibroblasts,
pubmed-meshheading:19950288-Gene Expression,
pubmed-meshheading:19950288-Humans,
pubmed-meshheading:19950288-Hydrocortisone,
pubmed-meshheading:19950288-Integrin alpha5,
pubmed-meshheading:19950288-Male,
pubmed-meshheading:19950288-Mice,
pubmed-meshheading:19950288-Mice, SCID,
pubmed-meshheading:19950288-RNA, Small Interfering,
pubmed-meshheading:19950288-RNA Interference,
pubmed-meshheading:19950288-Signal Transduction,
pubmed-meshheading:19950288-Synovial Membrane,
pubmed-meshheading:19950288-Testosterone
|
|
pubmed:year |
2009
|
|
pubmed:articleTitle |
Glucocorticoids increase alpha5 integrin expression and adhesion of synovial fibroblasts but inhibit ERK signaling, migration, and cartilage invasion.
|
|
pubmed:affiliation |
Department of Internal Medicine I, University Hospital of Regensburg, University of Regensburg, Regensburg, Germany.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
