Linked Life Data

19911861

Source:http://linkedlifedata.com/resource/pubmed/id/19911861

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
16
pubmed:dateCreated
2009-11-16
pubmed:abstractText
We propose a new mechanism for robust biological patterning. The mechanism bears analogy to interface dynamics in condensed media. We apply this method to study how gene networks control segmentation of Drosophila. The proposed model is minimal involving only 4 genes and a morphogen gradient. We discuss experimental data for which developmental genes are expressed within domains spatially limited by kinks (interfaces) and the gene interaction scheme contains both weak and strong repulsion. We show how kink-kink interactions can be calculated from the gene interactions and how the gene interaction scheme ensures the control of proportions (size regulation).
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1079-7114
pubmed:author
pubmed:issnType
Electronic
pubmed:day
16
pubmed:volume
103
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
168102
pubmed:dateRevised
2011-9-26
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Size regulation in the segmentation of Drosophila: interacting interfaces between localized domains of gene expression ensure robust spatial patterning.
pubmed:affiliation
Institute of Mechanical Engineering Problems, Institute of Print, St. Petersburg, Russia.
pubmed:publicationType
Journal Article