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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
35
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pubmed:dateCreated |
2009-12-9
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pubmed:abstractText |
Methotrexate plasma concentration is related to its clinical effects. Our aim was to identify the genetic basis of interindividual variability in methotrexate pharmacokinetics in children with newly diagnosed acute lymphoblastic leukemia (ALL).
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1527-7755
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pubmed:author |
pubmed-author:ChanDianaD,
pubmed-author:EvansWilliam EWE,
pubmed-author:GiacominiKathleen MKM,
pubmed-author:PanettaJohn CJC,
pubmed-author:PeiDeqingD,
pubmed-author:PuiChing-HonCH,
pubmed-author:RellingMary VMV,
pubmed-author:ShimasakiNorikoN,
pubmed-author:SparreboomAlexA,
pubmed-author:TreviñoLisa RLR,
pubmed-author:XXX,
pubmed-author:YangWenjianW
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pubmed:issnType |
Electronic
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pubmed:day |
10
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
5972-8
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pubmed:dateRevised |
2010-12-14
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pubmed:meshHeading |
pubmed-meshheading:19901119-Adolescent,
pubmed-meshheading:19901119-Antimetabolites, Antineoplastic,
pubmed-meshheading:19901119-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:19901119-Child,
pubmed-meshheading:19901119-Child, Preschool,
pubmed-meshheading:19901119-Female,
pubmed-meshheading:19901119-Gastrointestinal Diseases,
pubmed-meshheading:19901119-Genetic Predisposition to Disease,
pubmed-meshheading:19901119-Genome-Wide Association Study,
pubmed-meshheading:19901119-Germ-Line Mutation,
pubmed-meshheading:19901119-Humans,
pubmed-meshheading:19901119-Infant,
pubmed-meshheading:19901119-Linear Models,
pubmed-meshheading:19901119-Linkage Disequilibrium,
pubmed-meshheading:19901119-Logistic Models,
pubmed-meshheading:19901119-Male,
pubmed-meshheading:19901119-Methotrexate,
pubmed-meshheading:19901119-Organic Anion Transporters,
pubmed-meshheading:19901119-Phenotype,
pubmed-meshheading:19901119-Polymorphism, Single Nucleotide,
pubmed-meshheading:19901119-Precursor Cell Lymphoblastic Leukemia-Lymphoma,
pubmed-meshheading:19901119-Prospective Studies,
pubmed-meshheading:19901119-Risk Assessment,
pubmed-meshheading:19901119-Risk Factors,
pubmed-meshheading:19901119-Treatment Outcome
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pubmed:year |
2009
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pubmed:articleTitle |
Germline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects.
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pubmed:affiliation |
St Jude Children's Research Hospital, Memphis, TN 38105-2794, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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