|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0033860,
umls-concept:C0037083,
umls-concept:C0087111,
umls-concept:C0205253,
umls-concept:C0208973,
umls-concept:C0301625,
umls-concept:C0384648,
umls-concept:C0717758,
umls-concept:C0812246,
umls-concept:C0871261,
umls-concept:C1517892,
umls-concept:C1704419,
umls-concept:C1704632,
umls-concept:C1704666,
umls-concept:C1706817,
umls-concept:C1710082,
umls-concept:C2911692
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
2009-11-9
|
|
pubmed:abstractText |
TNF inhibitors have revolutionized the treatment of psoriasis vulgaris as well as psoriatic and rheumatoid arthritis and Crohn disease. Despite our understanding that these agents block TNF, their complex mechanism of action in disease resolution is still unclear.
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pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
1097-6825
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
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pubmed:volume |
124
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
1022-10.e1-395
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|
pubmed:dateRevised |
2010-12-3
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|
pubmed:meshHeading |
pubmed-meshheading:19895991-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:19895991-Dendritic Cells,
pubmed-meshheading:19895991-Down-Regulation,
pubmed-meshheading:19895991-Gene Expression,
pubmed-meshheading:19895991-Gene Expression Profiling,
pubmed-meshheading:19895991-Humans,
pubmed-meshheading:19895991-Immunoglobulin G,
pubmed-meshheading:19895991-Interferon-gamma,
pubmed-meshheading:19895991-Interleukin-17,
pubmed-meshheading:19895991-Interleukin-1beta,
pubmed-meshheading:19895991-Interleukin-8,
pubmed-meshheading:19895991-Myeloid Cells,
pubmed-meshheading:19895991-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:19895991-Psoriasis,
pubmed-meshheading:19895991-Receptors, Tumor Necrosis Factor,
pubmed-meshheading:19895991-Signal Transduction,
pubmed-meshheading:19895991-Skin,
pubmed-meshheading:19895991-T-Lymphocytes, Helper-Inducer,
pubmed-meshheading:19895991-Tumor Necrosis Factor-alpha,
pubmed-meshheading:19895991-Up-Regulation
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|
pubmed:year |
2009
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|
pubmed:articleTitle |
Effective treatment of psoriasis with etanercept is linked to suppression of IL-17 signaling, not immediate response TNF genes.
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|
pubmed:affiliation |
Laboratory for Investigative Dermatology, Rockefeller University, New York, NY 10065, USA.
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|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|
