Linked Life Data

19895216

Source:http://linkedlifedata.com/resource/pubmed/id/19895216

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2009-11-9
pubmed:abstractText
The Gram-positive species Enterococcus faecium has long been thought of as a harmless commensal of the mammalian GI tract. In the last two decades, however, E. faecium has become an important cause of nosocomial bacteremias. These infections are often difficult to treat owing to the resistance of E. faecium to a large number of antibiotics. In this article, we review the recent transition of E. faecium from commensal to nosocomial pathogen. We focus on population biology-based studies, which suggest that several clonal populations of E. faecium are mostly responsible for causing infections. We also discuss the role of the accessory genome of E. faecium in contributing to the infectious phenotype and examine the role that surface proteins of E. faecium may have in colonization and infection.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1746-0921
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1125-35
pubmed:dateRevised
2010-12-30
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Transition of Enterococcus faecium from commensal organism to nosocomial pathogen.
pubmed:affiliation
Department of Medical Microbiology, University Medical Center Utrecht, Heidelberglaan, CX Utrecht, The Netherlands. rwillems@umcutrecht.nl
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't