| pubmed-article:19875126 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19875126 | lifeskim:mentions | umls-concept:C0035647 | lld:lifeskim |
| pubmed-article:19875126 | lifeskim:mentions | umls-concept:C0026339 | lld:lifeskim |
| pubmed-article:19875126 | lifeskim:mentions | umls-concept:C0015733 | lld:lifeskim |
| pubmed-article:19875126 | lifeskim:mentions | umls-concept:C0005516 | lld:lifeskim |
| pubmed-article:19875126 | lifeskim:mentions | umls-concept:C1511790 | lld:lifeskim |
| pubmed-article:19875126 | lifeskim:mentions | umls-concept:C1527249 | lld:lifeskim |
| pubmed-article:19875126 | lifeskim:mentions | umls-concept:C0872252 | lld:lifeskim |
| pubmed-article:19875126 | lifeskim:mentions | umls-concept:C0591833 | lld:lifeskim |
| pubmed-article:19875126 | pubmed:issue | 19 | lld:pubmed |
| pubmed-article:19875126 | pubmed:dateCreated | 2010-4-19 | lld:pubmed |
| pubmed-article:19875126 | pubmed:abstractText | Tumor related products shed into the feces offer a potential source of biomarkers for the detection of colorectal cancer (CRC). Using SDS-PAGE followed by nanoflow reversed-phased LC-MS/MS to analyse fecal samples from Apc(Min/+) mice (that develop spontaneous multiple intestinal neoplasia with age) we have identified 336 proteins (115 proteins of murine origin, 201 from fecal bacteria, 18 associated with food intake and 2 of apparent parasitic origin). 75% of the murine proteins identified in this study are predicted to be extracellular or associated with the cell plasma membrane. Of these proteins, a number of the murine homologues of colorectal cancer associated proteins (CCAP) such as hemoglobin, haptoglobin, hemopexin, alpha-2-macroglobulin and cadherin-17 have been identified, demonstrating the potential of fecal proteomics for detecting potential biomarkers and paving the way for subsequent MS/MS based biomarker studies on similar human samples. | lld:pubmed |
| pubmed-article:19875126 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19875126 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19875126 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19875126 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19875126 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19875126 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19875126 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19875126 | pubmed:month | May | lld:pubmed |
| pubmed-article:19875126 | pubmed:issn | 1873-3778 | lld:pubmed |
| pubmed-article:19875126 | pubmed:author | pubmed-author:NiceEdouard... | lld:pubmed |
| pubmed-article:19875126 | pubmed:author | pubmed-author:BurgessAntony... | lld:pubmed |
| pubmed-article:19875126 | pubmed:author | pubmed-author:RothackerJuli... | lld:pubmed |
| pubmed-article:19875126 | pubmed:author | pubmed-author:AngChing-Seng... | lld:pubmed |
| pubmed-article:19875126 | pubmed:author | pubmed-author:PatsiourasHea... | lld:pubmed |
| pubmed-article:19875126 | pubmed:copyrightInfo | Copyright (c) 2009 Elsevier B.V. All rights reserved. | lld:pubmed |
| pubmed-article:19875126 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19875126 | pubmed:day | 7 | lld:pubmed |
| pubmed-article:19875126 | pubmed:volume | 1217 | lld:pubmed |
| pubmed-article:19875126 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19875126 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19875126 | pubmed:pagination | 3330-40 | lld:pubmed |
| pubmed-article:19875126 | pubmed:meshHeading | pubmed-meshheading:19875126... | lld:pubmed |
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| pubmed-article:19875126 | pubmed:meshHeading | pubmed-meshheading:19875126... | lld:pubmed |
| pubmed-article:19875126 | pubmed:meshHeading | pubmed-meshheading:19875126... | lld:pubmed |
| pubmed-article:19875126 | pubmed:meshHeading | pubmed-meshheading:19875126... | lld:pubmed |
| pubmed-article:19875126 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:19875126 | pubmed:articleTitle | Murine fecal proteomics: a model system for the detection of potential biomarkers for colorectal cancer. | lld:pubmed |
| pubmed-article:19875126 | pubmed:affiliation | Ludwig Institute for Cancer Research, Melbourne Tumour Biology Branch, PO Box 2008, Royal Melbourne Hospital, Australia. | lld:pubmed |
| pubmed-article:19875126 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19875126 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
