| pubmed-article:19846344 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19846344 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:19846344 | lifeskim:mentions | umls-concept:C0003873 | lld:lifeskim |
| pubmed-article:19846344 | lifeskim:mentions | umls-concept:C0087111 | lld:lifeskim |
| pubmed-article:19846344 | lifeskim:mentions | umls-concept:C0021403 | lld:lifeskim |
| pubmed-article:19846344 | lifeskim:mentions | umls-concept:C1456820 | lld:lifeskim |
| pubmed-article:19846344 | lifeskim:mentions | umls-concept:C0036043 | lld:lifeskim |
| pubmed-article:19846344 | lifeskim:mentions | umls-concept:C2368628 | lld:lifeskim |
| pubmed-article:19846344 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:19846344 | pubmed:dateCreated | 2010-2-4 | lld:pubmed |
| pubmed-article:19846344 | pubmed:abstractText | Twenty-eight patients with low-moderate, stable rheumatoid arthritis (RA), under treatment with tumor necrosis factor (TNF) alpha blockers, were immunized at least once with non-adjuvanted trivalent influenza vaccine during three consecutive influenza seasons. Antibodies toward A influenza antigens significantly increased and reached protective levels, still detectable 6 months after vaccination, both in RA patients and healthy controls. Response to B antigen instead was only observed from the second year for healthy controls and in the third year for patients. No significant difference in disease activity and anti-nuclear antibodies was observed as a consequence of vaccine administration, whereas T regulatory cells showed a significant increase 30 days after immunization in RA patients. This study confirms safety of influenza vaccine administration in RA patients treated with TNFalpha blockers. The cohort follow-up revealed the overcoming of poor B vaccine antigen immunogenicity via repeated vaccinations. Finally, protective antibody response was still observed 6 months after vaccination. | lld:pubmed |
| pubmed-article:19846344 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19846344 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19846344 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19846344 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19846344 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19846344 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19846344 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19846344 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19846344 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19846344 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19846344 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19846344 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19846344 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19846344 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19846344 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19846344 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19846344 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:19846344 | pubmed:issn | 1521-7035 | lld:pubmed |
| pubmed-article:19846344 | pubmed:author | pubmed-author:RossiFF | lld:pubmed |
| pubmed-article:19846344 | pubmed:author | pubmed-author:DonatelliII | lld:pubmed |
| pubmed-article:19846344 | pubmed:author | pubmed-author:PodestàEE | lld:pubmed |
| pubmed-article:19846344 | pubmed:author | pubmed-author:FacchiniMM | lld:pubmed |
| pubmed-article:19846344 | pubmed:author | pubmed-author:BiselliRR | lld:pubmed |
| pubmed-article:19846344 | pubmed:author | pubmed-author:NisiniRR | lld:pubmed |
| pubmed-article:19846344 | pubmed:author | pubmed-author:Di RosaRR | lld:pubmed |
| pubmed-article:19846344 | pubmed:author | pubmed-author:GermannWW | lld:pubmed |
| pubmed-article:19846344 | pubmed:author | pubmed-author:Di MartinoAA | lld:pubmed |
| pubmed-article:19846344 | pubmed:author | pubmed-author:LaganáAA | lld:pubmed |
| pubmed-article:19846344 | pubmed:author | pubmed-author:SalemiSS | lld:pubmed |
| pubmed-article:19846344 | pubmed:author | pubmed-author:TabaccoFF | lld:pubmed |
| pubmed-article:19846344 | pubmed:author | pubmed-author:AmodeoRR | lld:pubmed |
| pubmed-article:19846344 | pubmed:author | pubmed-author:FerlitoCC | lld:pubmed |
| pubmed-article:19846344 | pubmed:author | pubmed-author:MilanettiFF | lld:pubmed |
| pubmed-article:19846344 | pubmed:author | pubmed-author:D AmelioRR | lld:pubmed |
| pubmed-article:19846344 | pubmed:author | pubmed-author:Picchianti-Di... | lld:pubmed |
| pubmed-article:19846344 | pubmed:author | pubmed-author:CappellaAA | lld:pubmed |
| pubmed-article:19846344 | pubmed:copyrightInfo | Copyright 2009 Elsevier Inc. All rights reserved. | lld:pubmed |
| pubmed-article:19846344 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19846344 | pubmed:volume | 134 | lld:pubmed |
| pubmed-article:19846344 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19846344 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19846344 | pubmed:pagination | 113-20 | lld:pubmed |
| pubmed-article:19846344 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
| pubmed-article:19846344 | pubmed:meshHeading | pubmed-meshheading:19846344... | lld:pubmed |
| pubmed-article:19846344 | pubmed:meshHeading | pubmed-meshheading:19846344... | lld:pubmed |
| pubmed-article:19846344 | pubmed:meshHeading | pubmed-meshheading:19846344... | lld:pubmed |
| pubmed-article:19846344 | pubmed:meshHeading | pubmed-meshheading:19846344... | lld:pubmed |
| pubmed-article:19846344 | pubmed:meshHeading | pubmed-meshheading:19846344... | lld:pubmed |
| pubmed-article:19846344 | pubmed:meshHeading | pubmed-meshheading:19846344... | lld:pubmed |
| pubmed-article:19846344 | pubmed:meshHeading | pubmed-meshheading:19846344... | lld:pubmed |
| pubmed-article:19846344 | pubmed:meshHeading | pubmed-meshheading:19846344... | lld:pubmed |
| pubmed-article:19846344 | pubmed:meshHeading | pubmed-meshheading:19846344... | lld:pubmed |
| pubmed-article:19846344 | pubmed:meshHeading | pubmed-meshheading:19846344... | lld:pubmed |
| pubmed-article:19846344 | pubmed:meshHeading | pubmed-meshheading:19846344... | lld:pubmed |
| pubmed-article:19846344 | pubmed:meshHeading | pubmed-meshheading:19846344... | lld:pubmed |
| pubmed-article:19846344 | pubmed:meshHeading | pubmed-meshheading:19846344... | lld:pubmed |
| pubmed-article:19846344 | pubmed:meshHeading | pubmed-meshheading:19846344... | lld:pubmed |
| pubmed-article:19846344 | pubmed:meshHeading | pubmed-meshheading:19846344... | lld:pubmed |
| pubmed-article:19846344 | pubmed:meshHeading | pubmed-meshheading:19846344... | lld:pubmed |
| pubmed-article:19846344 | pubmed:meshHeading | pubmed-meshheading:19846344... | lld:pubmed |
| pubmed-article:19846344 | pubmed:meshHeading | pubmed-meshheading:19846344... | lld:pubmed |
| pubmed-article:19846344 | pubmed:meshHeading | pubmed-meshheading:19846344... | lld:pubmed |
| pubmed-article:19846344 | pubmed:meshHeading | pubmed-meshheading:19846344... | lld:pubmed |
| pubmed-article:19846344 | pubmed:meshHeading | pubmed-meshheading:19846344... | lld:pubmed |
| pubmed-article:19846344 | pubmed:meshHeading | pubmed-meshheading:19846344... | lld:pubmed |
| pubmed-article:19846344 | pubmed:meshHeading | pubmed-meshheading:19846344... | lld:pubmed |
| pubmed-article:19846344 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:19846344 | pubmed:articleTitle | Influenza vaccine administration in rheumatoid arthritis patients under treatment with TNFalpha blockers: safety and immunogenicity. | lld:pubmed |
| pubmed-article:19846344 | pubmed:affiliation | Sapienza Università di Roma, II Facoltà di Medicina e Chirurgia, A.O. S. Andrea, Via di Grottarossa 1039, Roma 00189, Italy. | lld:pubmed |
| pubmed-article:19846344 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19846344 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:19846344 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:19846344 | lld:pubmed |
