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rdf:type |
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lifeskim:mentions |
|
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pubmed:issue |
2
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pubmed:dateCreated |
2010-2-5
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pubmed:abstractText |
We examined two genetic markers established early in colorectal tumor development, microsatellite instability (MSI) and mutation of the KRAS proto-oncogene, to see if these genetic changes influence metastatic disease progression and survival.
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pubmed:grant |
|
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Feb
|
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pubmed:issn |
1534-4681
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
17
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pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
416-24
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pubmed:meshHeading |
pubmed-meshheading:19813061-Adenocarcinoma,
pubmed-meshheading:19813061-Adult,
pubmed-meshheading:19813061-Aged,
pubmed-meshheading:19813061-Aged, 80 and over,
pubmed-meshheading:19813061-Colon,
pubmed-meshheading:19813061-Colorectal Neoplasms,
pubmed-meshheading:19813061-Disease Progression,
pubmed-meshheading:19813061-Female,
pubmed-meshheading:19813061-Follow-Up Studies,
pubmed-meshheading:19813061-Genetic Markers,
pubmed-meshheading:19813061-Humans,
pubmed-meshheading:19813061-Male,
pubmed-meshheading:19813061-Microsatellite Instability,
pubmed-meshheading:19813061-Middle Aged,
pubmed-meshheading:19813061-Mutation,
pubmed-meshheading:19813061-Proto-Oncogene Proteins,
pubmed-meshheading:19813061-Rectum,
pubmed-meshheading:19813061-Survival Rate,
pubmed-meshheading:19813061-Treatment Outcome,
pubmed-meshheading:19813061-Young Adult,
pubmed-meshheading:19813061-ras Proteins
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pubmed:year |
2010
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pubmed:articleTitle |
KRAS mutation and microsatellite instability: two genetic markers of early tumor development that influence the prognosis of colorectal cancer.
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pubmed:affiliation |
Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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