Linked Life Data

19801477

Source:http://linkedlifedata.com/resource/pubmed/id/19801477

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
23
pubmed:dateCreated
2009-11-20
pubmed:abstractText
The aim of this study was to develop a test system to evaluate the effectiveness of procedures for decontamination of respirators contaminated with viral droplets. MS2 coliphage was used as a surrogate for pathogenic viruses. A viral droplet test system was constructed, and the size distribution of viral droplets loaded directly onto respirators was characterized using an aerodynamic particle sizer. The sizes ranged from 0.5 to 15 mum, and the sizes of the majority of the droplets were the range from 0.74 to 3.5 mum. The results also showed that the droplet test system generated similar droplet concentrations (particle counts) at different respirator locations. The test system was validated by studying the relative efficiencies of decontamination of sodium hypochlorite (bleach) and UV irradiation with droplets containing MS2 virus on filtering facepiece respirators. It was hypothesized that more potent decontamination treatments would result in corresponding larger decreases in the number of viable viruses recovered from the respirators. Sodium hypochlorite doses of 2.75 to 5.50 mg/liter with a 10-min decontamination period resulted in approximately 3- to 4-log reductions in the level of MS2 coliphage. When higher sodium hypochlorite doses (> or =8.25 mg/liter) were used with the same contact time that was used for the dilute solutions containing 2.75 to 5.50 mg/liter, all MS2 was inactivated. For UV decontamination at a wavelength of 254 nm, an approximately 3-log reduction in the level of MS2 virus was achieved with dose of 4.32 J/cm(2) (3 h of contact time with a UV intensity of 0.4 mW/cm(2)), while with higher doses of UV irradiation (> or =7.20 J/cm(2); UV intensity, 0.4 mW/cm(2); contact times, > or =5 h), all MS2 was inactivated. These findings may lead to development of a standard method to test decontamination of respirators challenged by viral droplets.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/19801477-10168531, http://linkedlifedata.com/resource/pubmed/commentcorrection/19801477-12737864, http://linkedlifedata.com/resource/pubmed/commentcorrection/19801477-12771070, http://linkedlifedata.com/resource/pubmed/commentcorrection/19801477-12867552, http://linkedlifedata.com/resource/pubmed/commentcorrection/19801477-15030699, http://linkedlifedata.com/resource/pubmed/commentcorrection/19801477-15202153, http://linkedlifedata.com/resource/pubmed/commentcorrection/19801477-15767002, http://linkedlifedata.com/resource/pubmed/commentcorrection/19801477-16313415, http://linkedlifedata.com/resource/pubmed/commentcorrection/19801477-1677653, http://linkedlifedata.com/resource/pubmed/commentcorrection/19801477-17283614, http://linkedlifedata.com/resource/pubmed/commentcorrection/19801477-18158720, http://linkedlifedata.com/resource/pubmed/commentcorrection/19801477-19139225, http://linkedlifedata.com/resource/pubmed/commentcorrection/19801477-5917337, http://linkedlifedata.com/resource/pubmed/commentcorrection/19801477-6018703, http://linkedlifedata.com/resource/pubmed/commentcorrection/19801477-7785996, http://linkedlifedata.com/resource/pubmed/commentcorrection/19801477-8254664
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1098-5336
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
75
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
7303-9
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Development of a test system to evaluate procedures for decontamination of respirators containing viral droplets.
pubmed:affiliation
National Institute for Occupational Safety and Health, National Personal Protective Technology Laboratory, Pittsburgh, PA 15236, USA.
pubmed:publicationType
Journal Article