Linked Life Data

19798462

Source:http://linkedlifedata.com/resource/pubmed/id/19798462

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2010-4-12
pubmed:abstractText
The validation of a method for the determination of chromium (Cr) in F-344/N rat tissues by inductively coupled plasma-mass spectrometry is described. Samples were analyzed after a rapid, open-vessel microwave digestion procedure. Performance of the method was evaluated using kidney tissue across a concentration range of 0.50-5.00 microg Cr/g tissue. Data for method linearity, accuracy, precision, digest stability, and storage stability are presented along with limits of detection and quantitation data. Data from a method cross-validation for B6C3F1 mouse kidney tissue are also presented. After validation, the method was applied to analyze samples collected in support of two chronic toxicity and carcinogenesis studies conducted by the National Toxicology Program.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1432-0703
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
58
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
883-91
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Validation and application of a method for the determination of total chromium in rat tissues by inductively coupled plasma mass spectrometry.
pubmed:affiliation
RTI International, Research Triangle Park, NC 27709, USA. levine@rti.org
pubmed:publicationType
Journal Article, Research Support, N.I.H., Extramural, Validation Studies