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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2009-12-17
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pubmed:abstractText |
Plasminogen activator inhibitor (PAI)-1 is increasingly recognized as a profibrotic factor but the mechanisms are not entirely clear. The present study examined the profibrotic mechanism of PAI-1 focusing on its effect on transforming growth factor (TGF)-beta1 in experimental diabetes.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Blood Glucose,
http://linkedlifedata.com/resource/pubmed/chemical/Collagen Type I,
http://linkedlifedata.com/resource/pubmed/chemical/Collagen Type IV,
http://linkedlifedata.com/resource/pubmed/chemical/Fibrinolysin,
http://linkedlifedata.com/resource/pubmed/chemical/Fibronectins,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 9,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Serpin E2,
http://linkedlifedata.com/resource/pubmed/chemical/Serpine2 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Serpins,
http://linkedlifedata.com/resource/pubmed/chemical/Transforming Growth Factor beta1
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pubmed:status |
MEDLINE
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pubmed:issn |
1421-9670
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2009 S. Karger AG, Basel.
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pubmed:issnType |
Electronic
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
481-90
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:19786738-Animals,
pubmed-meshheading:19786738-Blood Glucose,
pubmed-meshheading:19786738-Cell Line, Transformed,
pubmed-meshheading:19786738-Cells, Cultured,
pubmed-meshheading:19786738-Collagen Type I,
pubmed-meshheading:19786738-Collagen Type IV,
pubmed-meshheading:19786738-Diabetes Mellitus, Experimental,
pubmed-meshheading:19786738-Diabetic Nephropathies,
pubmed-meshheading:19786738-Feedback, Physiological,
pubmed-meshheading:19786738-Fibrinolysin,
pubmed-meshheading:19786738-Fibronectins,
pubmed-meshheading:19786738-Fibrosis,
pubmed-meshheading:19786738-Humans,
pubmed-meshheading:19786738-Male,
pubmed-meshheading:19786738-Matrix Metalloproteinase 9,
pubmed-meshheading:19786738-Mesangial Cells,
pubmed-meshheading:19786738-Mice,
pubmed-meshheading:19786738-Mice, Inbred C57BL,
pubmed-meshheading:19786738-Mice, Knockout,
pubmed-meshheading:19786738-Osmotic Pressure,
pubmed-meshheading:19786738-Promoter Regions, Genetic,
pubmed-meshheading:19786738-Proteinuria,
pubmed-meshheading:19786738-RNA, Messenger,
pubmed-meshheading:19786738-Serpin E2,
pubmed-meshheading:19786738-Serpins,
pubmed-meshheading:19786738-Transforming Growth Factor beta1
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pubmed:year |
2009
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pubmed:articleTitle |
Positive feedback loop between plasminogen activator inhibitor-1 and transforming growth factor-beta1 during renal fibrosis in diabetes.
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pubmed:affiliation |
Department of Bioinspired Science, Division of Life and Pharmaceutical Sciences, and College of Pharmacy, Ewha Womans University, Seoul, Korea.
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pubmed:publicationType |
Journal Article
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