19783717

Source:http://linkedlifedata.com/resource/pubmed/id/19783717

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0026882, umls-concept:C0599882, umls-concept:C0936012, umls-concept:C1511790, umls-concept:C1527249, umls-concept:C1537502
pubmed:issue	10
pubmed:dateCreated	2009-9-28
pubmed:abstractText	Mutation of the KRAS gene predicts the clinical response to the monoclonal antibody cetuximab in patients with advanced colorectal cancer (CRC). This study aimed to perform KRAS mutation detection on formalin-fixed paraffin-embedded (FFPE) tumour tissue by two different methods for comparison.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0376601
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal, http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents, http://linkedlifedata.com/resource/pubmed/chemical/DNA, Neoplasm, http://linkedlifedata.com/resource/pubmed/chemical/cetuximab
pubmed:status	MEDLINE
pubmed:month	Oct
pubmed:issn	1472-4146
pubmed:author	pubmed-author:FajoGG, pubmed-author:LawF B FFB, pubmed-author:MaE S KES, pubmed-author:SilMM, pubmed-author:WongC L PCL
pubmed:issnType	Electronic
pubmed:volume	62
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	886-91
pubmed:meshHeading	pubmed-meshheading:19783717-Adult, pubmed-meshheading:19783717-Aged, pubmed-meshheading:19783717-Aged, 80 and over, pubmed-meshheading:19783717-Antibodies, Monoclonal, pubmed-meshheading:19783717-Antineoplastic Agents, pubmed-meshheading:19783717-Base Sequence, pubmed-meshheading:19783717-Colorectal Neoplasms, pubmed-meshheading:19783717-DNA, Neoplasm, pubmed-meshheading:19783717-DNA Mutational Analysis, pubmed-meshheading:19783717-Female, pubmed-meshheading:19783717-Genes, ras, pubmed-meshheading:19783717-Humans, pubmed-meshheading:19783717-Male, pubmed-meshheading:19783717-Middle Aged, pubmed-meshheading:19783717-Mutation, pubmed-meshheading:19783717-Nucleic Acid Denaturation, pubmed-meshheading:19783717-Paraffin Embedding, pubmed-meshheading:19783717-Reproducibility of Results, pubmed-meshheading:19783717-Transition Temperature
pubmed:year	2009
pubmed:articleTitle	Detection of KRAS mutations in colorectal cancer by high-resolution melting analysis.
pubmed:affiliation	Division of Molecular Pathology, Department of Pathology, Hong Kong Sanatorium and Hospital, Happy Valley, Hong Kong, China. eskma@hksh.com
pubmed:publicationType	Journal Article, Comparative Study, Evaluation Studies