19767566

Source:http://linkedlifedata.com/resource/pubmed/id/19767566

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0384648, umls-concept:C0542341
pubmed:issue	7
pubmed:dateCreated	2009-9-21
pubmed:abstractText	Inflammation appears to be a necessity for both metastasis and elimination of tumor cells. IL-17, a proinflammatory cytokine produced by Th17 cells, contributes to both the processes by playing a dual role in the antitumor immunity. On one hand, IL-17 promotes an antitumor cytotoxic T cell response leading to tumor regression. On the other hand, by facilitating angiogenesis and egress of tumor cells from the primary focus, IL-17 promotes tumor growth. Thus, the therapeutic application that uses IL-17 needs to be refined by minimizing its protumor functions.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/2985117R
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-17
pubmed:status	MEDLINE
pubmed:month	Oct
pubmed:issn	1550-6606
pubmed:author	pubmed-author:MurugaiyanGopalG, pubmed-author:SahaBhaskarB
pubmed:issnType	Electronic
pubmed:day	1
pubmed:volume	183
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	4169-75
pubmed:meshHeading	pubmed-meshheading:19767566-Animals, pubmed-meshheading:19767566-Humans, pubmed-meshheading:19767566-Interleukin-17, pubmed-meshheading:19767566-Neoplasms, pubmed-meshheading:19767566-T-Lymphocytes, Helper-Inducer
pubmed:year	2009
pubmed:articleTitle	Protumor vs antitumor functions of IL-17.
pubmed:affiliation	Center for Neurologic Diseases, Brigham and Women's Hopsital and Harvard Medical School, Boston, MA 02120, USA.
pubmed:publicationType	Journal Article, Comparative Study, Review, Research Support, Non-U.S. Gov't