|
rdf:type |
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lifeskim:mentions |
umls-concept:C0007587,
umls-concept:C0033414,
umls-concept:C0041455,
umls-concept:C0109317,
umls-concept:C0598067,
umls-concept:C0752312,
umls-concept:C1150579,
umls-concept:C1306673,
umls-concept:C1333340,
umls-concept:C1366882,
umls-concept:C1370600,
umls-concept:C1704259,
umls-concept:C1705767,
umls-concept:C1705791,
umls-concept:C1705987,
umls-concept:C2756983
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|
pubmed:issue |
2
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|
pubmed:dateCreated |
2009-11-13
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|
pubmed:abstractText |
sPLA2 (secretory phospholipase A2) has been implicated in a wide range of cellular responses, including cell proliferation and ECM (extracellular matrix) remodelling. Even though ECM remodelling is an essential step for chondrogenesis, the expression and functions of sPLA2 during chondrogenesis have not been studied.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
|
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pubmed:issn |
1768-322X
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pubmed:author |
|
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pubmed:issnType |
Electronic
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pubmed:volume |
102
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
107-19
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pubmed:dateRevised |
2010-3-1
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pubmed:meshHeading |
pubmed-meshheading:19764901-Animals,
pubmed-meshheading:19764901-Apoptosis,
pubmed-meshheading:19764901-Avian Proteins,
pubmed-meshheading:19764901-Cell Differentiation,
pubmed-meshheading:19764901-Cells, Cultured,
pubmed-meshheading:19764901-Chick Embryo,
pubmed-meshheading:19764901-Chondrocytes,
pubmed-meshheading:19764901-Chondrogenesis,
pubmed-meshheading:19764901-Collagen Type I,
pubmed-meshheading:19764901-Enzyme Activation,
pubmed-meshheading:19764901-Extracellular Signal-Regulated MAP Kinases,
pubmed-meshheading:19764901-Gene Expression Regulation, Developmental,
pubmed-meshheading:19764901-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:19764901-MAP Kinase Signaling System,
pubmed-meshheading:19764901-Matrix Metalloproteinase 9,
pubmed-meshheading:19764901-Phospholipases A2, Secretory,
pubmed-meshheading:19764901-Time Factors
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pubmed:year |
2010
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pubmed:articleTitle |
Secretory phospholipase A2 promotes MMP-9-mediated cell death by degrading type I collagen via the ERK pathway at an early stage of chondrogenesis.
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pubmed:affiliation |
Department of Biology, College of Natural Sciences, Kyungpook National University, Daegu 702-701, Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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