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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2009-11-5
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pubmed:abstractText |
Human multidrug and toxin extrusion member 1, MATE1 (SLC47A1), plays an important role in the renal and biliary excretion of endogenous and exogenous organic cations including many therapeutic drugs. In this study, we characterized the transcriptional effects of five polymorphic variants and six common haplotypes in the basal promoter region of MATE1 that were identified in 272 DNA samples from ethnically diverse US populations.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1744-6872
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pubmed:author |
pubmed-author:AhituvNadavN,
pubmed-author:BlackBrain LBL,
pubmed-author:CastroRichard ARA,
pubmed-author:FerrinThomas ETE,
pubmed-author:GiacominiKathleen MKM,
pubmed-author:Goo LeeMinM,
pubmed-author:Ha ChoiJiJ,
pubmed-author:HesselsonStephanieS,
pubmed-author:Ho LeeJeongJ,
pubmed-author:JohnsSusan JSJ,
pubmed-author:KangJi-OneJO,
pubmed-author:KimMee JMJ,
pubmed-author:KwokPui-YanPY,
pubmed-author:NguyenLoanL,
pubmed-author:StrykeDougD,
pubmed-author:Wah YeeSookS
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pubmed:issnType |
Print
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
770-80
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pubmed:dateRevised |
2011-9-26
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pubmed:meshHeading |
pubmed-meshheading:19745787-Electrophoretic Mobility Shift Assay,
pubmed-meshheading:19745787-Genetic Variation,
pubmed-meshheading:19745787-Haplotypes,
pubmed-meshheading:19745787-Humans,
pubmed-meshheading:19745787-Kruppel-Like Transcription Factors,
pubmed-meshheading:19745787-Organic Cation Transport Proteins,
pubmed-meshheading:19745787-Polymorphism, Genetic,
pubmed-meshheading:19745787-Promoter Regions, Genetic,
pubmed-meshheading:19745787-Transcription Factor AP-1
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pubmed:year |
2009
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pubmed:articleTitle |
Identification and characterization of novel polymorphisms in the basal promoter of the human transporter, MATE1.
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pubmed:affiliation |
Department of Pharmacology, Ewha Womans University, Seoul, Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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