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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3-4
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pubmed:dateCreated |
2009-10-16
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pubmed:abstractText |
Tumor necrosis factor-alpha (TNF-alpha) is a pro-inflammatory cytokine that may act as an endogenous tumor promoter. A genetic polymorphism of TNF-alpha gene at position -308 promoter region is involved in the regulation of expression level and has been found to be associated with susceptibility to various types of cancer.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1877-783X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
261-4
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pubmed:dateRevised |
2011-6-17
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pubmed:meshHeading |
pubmed-meshheading:19683483-Adult,
pubmed-meshheading:19683483-Aged,
pubmed-meshheading:19683483-Aged, 80 and over,
pubmed-meshheading:19683483-Carcinoma, Hepatocellular,
pubmed-meshheading:19683483-Case-Control Studies,
pubmed-meshheading:19683483-Female,
pubmed-meshheading:19683483-Genetic Predisposition to Disease,
pubmed-meshheading:19683483-Humans,
pubmed-meshheading:19683483-Liver Neoplasms,
pubmed-meshheading:19683483-Male,
pubmed-meshheading:19683483-Middle Aged,
pubmed-meshheading:19683483-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:19683483-Polymorphism, Single Nucleotide,
pubmed-meshheading:19683483-Promoter Regions, Genetic,
pubmed-meshheading:19683483-Risk,
pubmed-meshheading:19683483-Tumor Necrosis Factor-alpha,
pubmed-meshheading:19683483-Turkey,
pubmed-meshheading:19683483-Young Adult
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pubmed:year |
2009
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pubmed:articleTitle |
G-308A TNF-alpha polymorphism is associated with an increased risk of hepatocellular carcinoma in the Turkish population: case-control study.
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pubmed:affiliation |
Department of Gastroenterology, Faculty of Medicine, Cukurova University, 01330 Adana, Turkey.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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