|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0006141,
umls-concept:C0010927,
umls-concept:C0012739,
umls-concept:C0017262,
umls-concept:C0027651,
umls-concept:C0059239,
umls-concept:C0185117,
umls-concept:C0333710,
umls-concept:C0334094,
umls-concept:C0549193,
umls-concept:C1334274,
umls-concept:C1512083,
umls-concept:C1516240,
umls-concept:C1565434,
umls-concept:C1707520,
umls-concept:C2911684
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|
pubmed:issue |
8
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|
pubmed:dateCreated |
2009-7-31
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|
pubmed:abstractText |
Focal adhesion kinase (FAK) is an enzyme of the tyrosine kinase group linked to signaling pathways between cells and the extracellular matrix. In tumor cells in vitro, FAK expression correlated with their ability for invasion and metastasis. Additionally, in vivo FAK has been implicated in malignant transformation and disease progression. The aim of the present study was to evaluate the clinical significance of FAK expression in breast ductal invasive carcinoma (DIC).
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
|
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pubmed:issn |
1643-3750
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|
pubmed:author |
|
|
pubmed:issnType |
Electronic
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pubmed:volume |
15
|
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pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
BR221-6
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:19644410-Adult,
pubmed-meshheading:19644410-Aged,
pubmed-meshheading:19644410-Aged, 80 and over,
pubmed-meshheading:19644410-Breast Neoplasms,
pubmed-meshheading:19644410-Carcinoma, Ductal, Breast,
pubmed-meshheading:19644410-Cell Proliferation,
pubmed-meshheading:19644410-Cytoplasm,
pubmed-meshheading:19644410-Female,
pubmed-meshheading:19644410-Focal Adhesion Protein-Tyrosine Kinases,
pubmed-meshheading:19644410-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:19644410-Humans,
pubmed-meshheading:19644410-Immunohistochemistry,
pubmed-meshheading:19644410-Middle Aged,
pubmed-meshheading:19644410-Neoplasm Invasiveness
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|
pubmed:year |
2009
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pubmed:articleTitle |
Focal adhesion kinase (FAK) immunocytochemical expression in breast ductal invasive carcinoma (DIC): correlation with clinicopathological parameters and tumor proliferative capacity.
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pubmed:affiliation |
Department of Tumor Biology, Section of Cytopathology, Institut Curie, Paris, France. theocharis@ath.forthnet.gr
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pubmed:publicationType |
Journal Article
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