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rdf:type |
|
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lifeskim:mentions |
umls-concept:C0018956,
umls-concept:C0020962,
umls-concept:C0026809,
umls-concept:C0040113,
umls-concept:C0040300,
umls-concept:C0040732,
umls-concept:C0086418,
umls-concept:C0205245,
umls-concept:C1413131,
umls-concept:C1417166,
umls-concept:C1517162,
umls-concept:C1527148,
umls-concept:C1552644,
umls-concept:C1823153,
umls-concept:C2349976
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|
pubmed:issue |
5
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|
pubmed:dateCreated |
2009-6-23
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|
pubmed:abstractText |
There is an increasing need for suitable animal models for the study of the human immune system and disease. The purpose of this study was to develop a practical in vivo model of human immune cell repopulation using ex vivo expanded human fetal liver-derived CD34(+) hematopoietic stem cells and subrenally coimplanted fetal liver/thymus tissues.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
|
|
pubmed:issn |
1873-2623
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pubmed:author |
pubmed-author:BärDopD,
pubmed-author:ChoiB-KBK,
pubmed-author:ChoiG SGS,
pubmed-author:IRAG HGHJr,
pubmed-author:JouYY,
pubmed-author:JungD YDY,
pubmed-author:JungG OGO,
pubmed-author:KangM JMJ,
pubmed-author:KwonC HCH,
pubmed-author:LeeS KSK,
pubmed-author:ParkJ BJB,
pubmed-author:ParkK SKS
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pubmed:issnType |
Electronic
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pubmed:volume |
41
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pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
1885-90
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pubmed:meshHeading |
pubmed-meshheading:19545750-Animals,
pubmed-meshheading:19545750-Antigens, CD34,
pubmed-meshheading:19545750-DNA-Binding Proteins,
pubmed-meshheading:19545750-Fetal Tissue Transplantation,
pubmed-meshheading:19545750-Flow Cytometry,
pubmed-meshheading:19545750-Hematopoietic Stem Cell Transplantation,
pubmed-meshheading:19545750-Humans,
pubmed-meshheading:19545750-Liver,
pubmed-meshheading:19545750-Liver Transplantation,
pubmed-meshheading:19545750-Lymphocyte Transfusion,
pubmed-meshheading:19545750-Mice,
pubmed-meshheading:19545750-Mice, Knockout,
pubmed-meshheading:19545750-Mice, SCID,
pubmed-meshheading:19545750-Subrenal Capsule Assay,
pubmed-meshheading:19545750-Thymus Gland,
pubmed-meshheading:19545750-Transplantation, Heterologous
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pubmed:year |
2009
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pubmed:articleTitle |
Development of functional human immune system with the transplantations of human fetal liver/thymus tissues and expanded hematopoietic stem cells in RAG2-/-gamma(c)-/- MICE.
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pubmed:affiliation |
Transplantation Research Center, Samsung Biomedical Research Institute, Seoul, Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
