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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2009-11-26
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pubmed:abstractText |
Cleavage of IGFBPs by proteases results in IGFBP fragments that have altered IGF-binding affinity, and IGF-independent roles. We have previously purified a specific IGFBP-1 protease activity from the urine of an individual with multiple myeloma and dermatitis. The aim of this study was to determine whether IGFBP-1 protease activity and/or IGFBP-1 fragments were present in the circulation of this patient.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1532-2238
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
507-12
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pubmed:meshHeading |
pubmed-meshheading:19539506-Aged,
pubmed-meshheading:19539506-Antimicrobial Cationic Peptides,
pubmed-meshheading:19539506-Biotinylation,
pubmed-meshheading:19539506-Blood Proteins,
pubmed-meshheading:19539506-Carrier Proteins,
pubmed-meshheading:19539506-Chromatography,
pubmed-meshheading:19539506-Dermatitis,
pubmed-meshheading:19539506-Female,
pubmed-meshheading:19539506-Humans,
pubmed-meshheading:19539506-Insulin-Like Growth Factor Binding Protein 1,
pubmed-meshheading:19539506-Insulin-Like Growth Factor I,
pubmed-meshheading:19539506-Multiple Myeloma,
pubmed-meshheading:19539506-Protein Isoforms,
pubmed-meshheading:19539506-Radioimmunoassay,
pubmed-meshheading:19539506-Recombinant Proteins,
pubmed-meshheading:19539506-Sepharose
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pubmed:year |
2009
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pubmed:articleTitle |
IGFBP-1 protease activity and IGFBP-1 fragments in a patient with multiple myeloma.
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pubmed:affiliation |
Department of Molecular Medicine and Surgery, Karolinska Institutet, L1:01 Karolinska University Hospital Solna, SE-171 76 Stockholm, Sweden.
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
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