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rdf:type |
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lifeskim:mentions |
umls-concept:C0006142,
umls-concept:C0017262,
umls-concept:C0031268,
umls-concept:C0032743,
umls-concept:C0069515,
umls-concept:C0087111,
umls-concept:C0185117,
umls-concept:C0242957,
umls-concept:C0392747,
umls-concept:C0443172,
umls-concept:C0520484,
umls-concept:C0567416,
umls-concept:C2911684
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pubmed:issue |
7
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pubmed:dateCreated |
2009-8-4
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pubmed:abstractText |
In vivo imaging of human epidermal growth factor receptor type 2 (HER2) expression may allow direct assessment of HER2 status in tumor tissue and provide a means to quantify changes in receptor expression after HER2-targeted therapies. This work describes the in vivo characterization of the HER2-specific N-2-(4-(18)F-fluorobenzamido)ethyl]maleimide ((18)F-FBEM)-Z(HER2:342) Affibody molecule and its application to study the effect of 17 (dimethylaminoethylamino)-17-demethoxygeldanamycin (17-DMAG) on HER2 expression by PET.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19525458-12088731,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19525458-15133471,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19525458-15659867,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19525458-15735035,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19525458-15791458,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19525458-15943788,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19525458-15994969,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19525458-16051028,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19525458-16175177,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19525458-16287254,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19525458-16538504,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19525458-16644749,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19525458-16644755,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19525458-16929116,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19525458-16929325,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19525458-17085641,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19525458-17332348,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19525458-17396141,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19525458-17512622,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19525458-17536171,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19525458-17944527,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19525458-17979560,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19525458-18048824,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19525458-18157531,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19525458-18201769,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19525458-18357367,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19525458-18413392,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19525458-3023921
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0161-5505
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1131-9
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pubmed:dateRevised |
2010-9-24
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pubmed:meshHeading |
pubmed-meshheading:19525458-Animals,
pubmed-meshheading:19525458-Antineoplastic Agents,
pubmed-meshheading:19525458-Breast Neoplasms,
pubmed-meshheading:19525458-Cell Line, Tumor,
pubmed-meshheading:19525458-Fluorine Radioisotopes,
pubmed-meshheading:19525458-Gene Expression Profiling,
pubmed-meshheading:19525458-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:19525458-Humans,
pubmed-meshheading:19525458-Isotope Labeling,
pubmed-meshheading:19525458-Metabolic Clearance Rate,
pubmed-meshheading:19525458-Mice,
pubmed-meshheading:19525458-Molecular Probe Techniques,
pubmed-meshheading:19525458-Positron-Emission Tomography,
pubmed-meshheading:19525458-Radiopharmaceuticals,
pubmed-meshheading:19525458-Receptor, erbB-2,
pubmed-meshheading:19525458-Tissue Distribution,
pubmed-meshheading:19525458-Treatment Outcome
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pubmed:year |
2009
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pubmed:articleTitle |
Changes in HER2 expression in breast cancer xenografts after therapy can be quantified using PET and (18)F-labeled affibody molecules.
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pubmed:affiliation |
National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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