|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
2009-4-21
|
|
pubmed:abstractText |
Tissue hypoxia after blood loss, replantation and flap reperfusion remains a challenging task in surgery. Normovolemic hemodilution improves hemorheologic properties without increasing oxygen carrying capacity. Red blood cell transfusion is the current standard of treatment with its attendant risks. The aim of this study was to investigate the potential of the chemically modified hemoglobin, MP4, to reduce skin flap necrosis and its effect on selected blood markers and kidneys.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
0949-2321
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
17
|
|
pubmed:volume |
14
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
123-9
|
|
pubmed:meshHeading |
pubmed-meshheading:19380283-Animals,
pubmed-meshheading:19380283-Cell Hypoxia,
pubmed-meshheading:19380283-Dextrans,
pubmed-meshheading:19380283-Disease Models, Animal,
pubmed-meshheading:19380283-Ear,
pubmed-meshheading:19380283-Hemodilution,
pubmed-meshheading:19380283-Hemoglobins,
pubmed-meshheading:19380283-Injections,
pubmed-meshheading:19380283-Leukocytes,
pubmed-meshheading:19380283-Maleimides,
pubmed-meshheading:19380283-Mice,
pubmed-meshheading:19380283-Mice, Hairless,
pubmed-meshheading:19380283-Necrosis,
pubmed-meshheading:19380283-Polyethylene Glycols,
pubmed-meshheading:19380283-Regional Blood Flow,
pubmed-meshheading:19380283-Skin,
pubmed-meshheading:19380283-Surgical Flaps
|
|
pubmed:year |
2009
|
|
pubmed:articleTitle |
Effects of maleimide-polyethylene glycol-modified human hemoglobin (MP4) on tissue necrosis in SKH1-hr hairless mice.
|
|
pubmed:affiliation |
Department of Plastic and Hand Surgery, Burn Center, Ruhr-University Bochum, Bochum, Germany. ole.goertz@rub.de
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
