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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2009-5-11
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pubmed:abstractText |
Pancreatic cancer is a devastating disease characterized by dismal 5-year survival rates and limited treatment options. In an effort to provide useful models for preclinical evaluation of new experimental therapeutics, we and others have developed orthotopic mouse models of pancreatic cancer. The utility of these models for pre-clinical testing is dependent upon quantitative, noninvasive methods for monitoring in vivo tumor progression in real time. Toward this goal, we performed whole-body fluorescence imaging and ultrasound imaging to evaluate and to compare these noninvasive imaging modalities for assessing tumor burden and tumor progression in an orthotopic mouse model of pancreatic cancer.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19351417-10935470,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19351417-11315094,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19351417-11888932,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19351417-12943825,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19351417-16024636,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19351417-1608975,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19351417-16210828,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19351417-16267005,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19351417-16338340,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19351417-16618743,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19351417-17406431,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19351417-17901144,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19351417-18215290,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19351417-18287387
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2407
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
106
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:19351417-Animals,
pubmed-meshheading:19351417-Cell Line, Tumor,
pubmed-meshheading:19351417-Diagnostic Imaging,
pubmed-meshheading:19351417-Disease Models, Animal,
pubmed-meshheading:19351417-Fluorescence,
pubmed-meshheading:19351417-Humans,
pubmed-meshheading:19351417-Luminescent Proteins,
pubmed-meshheading:19351417-Mice,
pubmed-meshheading:19351417-Mice, Nude,
pubmed-meshheading:19351417-Neoplasm Transplantation,
pubmed-meshheading:19351417-Pancreatic Neoplasms,
pubmed-meshheading:19351417-Tumor Burden,
pubmed-meshheading:19351417-Ultrasonography
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pubmed:year |
2009
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pubmed:articleTitle |
Complementarity of ultrasound and fluorescence imaging in an orthotopic mouse model of pancreatic cancer.
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pubmed:affiliation |
Moores UCSD Cancer Center, University of California, La Jolla, CA, USA. csnyder@ucsd.edu
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Evaluation Studies,
Research Support, N.I.H., Extramural
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