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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2009-5-15
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pubmed:abstractText |
Although aspirin treatment is useful in reducing ischaemic events in diabetic patients, recent studies suggest that it is less effective when compared with non-diabetics (ND). We sought to evaluate COX-1 sensitivity and thromboxane A(2) (TxA(2)) production in type 1 (T1DM) and type 2 diabetic (T2DM) patients under chronic aspirin treatment, and also evaluate the association between thromboxane A(2) (TxA(2)) production and markers of inflammation and metabolic control, such as high-sensitivity C-reactive protein, fasting blood glucose, and haemoglobin A1c (HbA1c).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1522-9645
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pubmed:author |
pubmed-author:BiasucciLuigi MLM,
pubmed-author:CreaFilippoF,
pubmed-author:Di RenzoLiviaL,
pubmed-author:GhirlandaGiovanniG,
pubmed-author:GiubilatoSimonaS,
pubmed-author:LeoAndreaA,
pubmed-author:LiuzzoGiovannaG,
pubmed-author:MattielloTeresaT,
pubmed-author:PitoccoDarioD,
pubmed-author:PulcinelliFabio MFM,
pubmed-author:RiondinoSilviaS,
pubmed-author:TrifiròElisabettaE
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pubmed:issnType |
Electronic
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1279-86
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pubmed:meshHeading |
pubmed-meshheading:19346231-Adult,
pubmed-meshheading:19346231-Aged,
pubmed-meshheading:19346231-Aspirin,
pubmed-meshheading:19346231-Blood Platelets,
pubmed-meshheading:19346231-C-Reactive Protein,
pubmed-meshheading:19346231-Case-Control Studies,
pubmed-meshheading:19346231-Cyclooxygenase 1,
pubmed-meshheading:19346231-Diabetes Mellitus, Type 1,
pubmed-meshheading:19346231-Diabetes Mellitus, Type 2,
pubmed-meshheading:19346231-Diabetic Angiopathies,
pubmed-meshheading:19346231-Drug Resistance,
pubmed-meshheading:19346231-Female,
pubmed-meshheading:19346231-Hemoglobin A, Glycosylated,
pubmed-meshheading:19346231-Humans,
pubmed-meshheading:19346231-Hyperglycemia,
pubmed-meshheading:19346231-Male,
pubmed-meshheading:19346231-Middle Aged,
pubmed-meshheading:19346231-Platelet Aggregation,
pubmed-meshheading:19346231-Platelet Aggregation Inhibitors,
pubmed-meshheading:19346231-Statistics, Nonparametric,
pubmed-meshheading:19346231-Thromboxane A2
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pubmed:year |
2009
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pubmed:articleTitle |
COX-1 sensitivity and thromboxane A2 production in type 1 and type 2 diabetic patients under chronic aspirin treatment.
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pubmed:affiliation |
Department of Experimental Medicine, Sapienza University of Rome, Viale Regina Elena 324, 00161 Rome, Italy. fabio.pulcinelli@uniroma1.it
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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