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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2009-4-7
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pubmed:abstractText |
Subclinical gut inflammation is common in spondylarthritis, but the immunologic abnormalities underlying this process are undefined. Perturbation of the interleukin-23 (IL-23)/Th17 axis has emerged as a fundamental trigger of chronic inflammation. This study was undertaken to investigate the expression and tissue distribution of IL-23/Th17-related molecules in Crohn's disease (CD) and in subclinical gut inflammation in ankylosing spondylitis (AS).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0004-3591
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pubmed:author |
pubmed-author:BombardieriMicheleM,
pubmed-author:CicciaFrancescoF,
pubmed-author:CraxiAntonioA,
pubmed-author:FrancoVitoV,
pubmed-author:GiardinaAnnaritaA,
pubmed-author:GiardinaEnnioE,
pubmed-author:PeraltaSergioS,
pubmed-author:PitzalisCostantinoC,
pubmed-author:PorcasiRossanaR,
pubmed-author:PrincipatoAlfonsoA,
pubmed-author:TrioloGiovanniG,
pubmed-author:TripodoClaudioC
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pubmed:issnType |
Print
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pubmed:volume |
60
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
955-65
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pubmed:meshHeading |
pubmed-meshheading:19333939-Adult,
pubmed-meshheading:19333939-Female,
pubmed-meshheading:19333939-Gene Expression,
pubmed-meshheading:19333939-Humans,
pubmed-meshheading:19333939-Ileitis,
pubmed-meshheading:19333939-Ileum,
pubmed-meshheading:19333939-Interleukin-17,
pubmed-meshheading:19333939-Interleukin-23 Subunit p19,
pubmed-meshheading:19333939-Intestinal Mucosa,
pubmed-meshheading:19333939-Male,
pubmed-meshheading:19333939-Middle Aged,
pubmed-meshheading:19333939-Monocytes,
pubmed-meshheading:19333939-Paneth Cells,
pubmed-meshheading:19333939-Prevalence,
pubmed-meshheading:19333939-RNA, Messenger,
pubmed-meshheading:19333939-STAT1 Transcription Factor,
pubmed-meshheading:19333939-Spondylitis, Ankylosing,
pubmed-meshheading:19333939-Th1 Cells,
pubmed-meshheading:19333939-Th2 Cells,
pubmed-meshheading:19333939-Up-Regulation
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pubmed:year |
2009
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pubmed:articleTitle |
Overexpression of interleukin-23, but not interleukin-17, as an immunologic signature of subclinical intestinal inflammation in ankylosing spondylitis.
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pubmed:affiliation |
University of Palermo, Palermo, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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