|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
1-2
|
|
pubmed:dateCreated |
2009-4-27
|
|
pubmed:abstractText |
T cells play a critical role in alloimmune recognition and thus contribute to graft-versus-host disease (GVHD) and relapse prevention in hematopoietic stem cell transplantation (HSCT). Cytotoxic T lymphocyte antigen-4 (CTLA-4) and inducible costimulator (ICOS) are costimulatory molecules of T cell activation and their genetic variations can affect the capacity of T cells to become activated or inactivated.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
1873-3492
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
403
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
229-33
|
|
pubmed:dateRevised |
2011-11-17
|
|
pubmed:meshHeading |
pubmed-meshheading:19332044-Antigens, CD,
pubmed-meshheading:19332044-Antigens, Differentiation, T-Lymphocyte,
pubmed-meshheading:19332044-CTLA-4 Antigen,
pubmed-meshheading:19332044-Female,
pubmed-meshheading:19332044-Genotype,
pubmed-meshheading:19332044-Graft vs Host Disease,
pubmed-meshheading:19332044-Hematopoietic Stem Cell Transplantation,
pubmed-meshheading:19332044-Humans,
pubmed-meshheading:19332044-Inducible T-Cell Co-Stimulator Protein,
pubmed-meshheading:19332044-Male,
pubmed-meshheading:19332044-Multivariate Analysis,
pubmed-meshheading:19332044-Polymorphism, Genetic,
pubmed-meshheading:19332044-Polymorphism, Single Nucleotide,
pubmed-meshheading:19332044-Recurrence,
pubmed-meshheading:19332044-Risk Factors,
pubmed-meshheading:19332044-Siblings,
pubmed-meshheading:19332044-Survival Rate,
pubmed-meshheading:19332044-Transplantation, Homologous,
pubmed-meshheading:19332044-Treatment Outcome
|
|
pubmed:year |
2009
|
|
pubmed:articleTitle |
Functional polymorphism of CTLA-4 and ICOS genes in allogeneic hematopoietic stem cell transplantation.
|
|
pubmed:affiliation |
Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei, Taiwan.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
