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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2009-3-3
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pubmed:abstractText |
Folic acid fortification has reduced neural tube defect prevalence by 50% to 70%. It is unlikely that fortification levels will be increased to reduce neural tube defect prevalence further. Therefore, it is important to identify other modifiable risk factors. Vitamin B(12) is metabolically related to folate; moreover, previous studies have found low B(12) status in mothers of children affected by neural tube defect. Our objective was to quantify the effect of low B(12) status on neural tube defect risk in a high-prevalence, unfortified population.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1098-4275
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
123
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
917-23
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pubmed:meshHeading |
pubmed-meshheading:19255021-Adult,
pubmed-meshheading:19255021-Case-Control Studies,
pubmed-meshheading:19255021-Cohort Studies,
pubmed-meshheading:19255021-Cross-Sectional Studies,
pubmed-meshheading:19255021-Female,
pubmed-meshheading:19255021-Folic Acid,
pubmed-meshheading:19255021-Humans,
pubmed-meshheading:19255021-Infant, Newborn,
pubmed-meshheading:19255021-Ireland,
pubmed-meshheading:19255021-Neural Tube Defects,
pubmed-meshheading:19255021-Pregnancy,
pubmed-meshheading:19255021-Pregnancy Complications,
pubmed-meshheading:19255021-Pregnancy Trimester, Second,
pubmed-meshheading:19255021-Prenatal Care,
pubmed-meshheading:19255021-Recurrence,
pubmed-meshheading:19255021-Risk,
pubmed-meshheading:19255021-Vitamin B 12,
pubmed-meshheading:19255021-Vitamin B 12 Deficiency,
pubmed-meshheading:19255021-Young Adult
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pubmed:year |
2009
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pubmed:articleTitle |
Maternal vitamin B12 status and risk of neural tube defects in a population with high neural tube defect prevalence and no folic Acid fortification.
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pubmed:affiliation |
Schools of Medicine, Trinity College Dublin, School of Medicine, Dublin 2, Ireland. amolloy@tcd.ie
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Intramural
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