Linked Life Data

19199814

Source:http://linkedlifedata.com/resource/pubmed/id/19199814

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2009-2-20
pubmed:abstractText
Investigators of wildlife populations often utilize demographic indicators to understand the relationship between habitat characteristics and population viability. Assessments of corticosterone may enable earlier detection of populations at risk of decline because physiological adjustments to habitat disturbance occur before reproductive diminutions. Noninvasive methods to accomplish these assessments are important in species of concern, such as the greater sage grouse (GRSG). Therefore, we validated a radioimmunoassay that measures immunoreactive corticosterone metabolites (ICM) in fecal samples and used it to characterize the adrenocortical response of 15 GRSG exposed to capture, intravenous injection of 50 IU/kg adrenocorticotrophic hormone (ACTH) or saline, and 22 h of confinement. Those animals injected with ACTH exhibited a more sustained (P = 0.0139) and less variable (P = 0.0012) response than those injected with saline, indicating different levels of adrenocortical activity. We also found that potential field-collection protocols of fecal samples did not alter ICM concentrations: samples held at 4 degrees C for up to 16 h contained similar levels of ICM as those frozen (-20 degrees C) immediately. This study demonstrates a multiphasic adrenocortical response that varied with the level of stimulation and indicates that the assay used to measure this phenomenon is applicable for studies of wild GRSG.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/19199814-10696570, http://linkedlifedata.com/resource/pubmed/commentcorrection/19199814-11121291, http://linkedlifedata.com/resource/pubmed/commentcorrection/19199814-11765979, http://linkedlifedata.com/resource/pubmed/commentcorrection/19199814-12614627, http://linkedlifedata.com/resource/pubmed/commentcorrection/19199814-12714017, http://linkedlifedata.com/resource/pubmed/commentcorrection/19199814-15364201, http://linkedlifedata.com/resource/pubmed/commentcorrection/19199814-15811363, http://linkedlifedata.com/resource/pubmed/commentcorrection/19199814-15891021, http://linkedlifedata.com/resource/pubmed/commentcorrection/19199814-16055842, http://linkedlifedata.com/resource/pubmed/commentcorrection/19199814-16055845, http://linkedlifedata.com/resource/pubmed/commentcorrection/19199814-16055847, http://linkedlifedata.com/resource/pubmed/commentcorrection/19199814-17312759
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1537-5293
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
82
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
190-201
pubmed:dateRevised
2010-9-23
pubmed:meshHeading
pubmed:articleTitle
The adrenocortical response of greater sage grouse (Centrocercus urophasianus) to capture, ACTH injection, and confinement, as measured in fecal samples.
pubmed:affiliation
Zoology Department and Molecular and Environmental Toxicology Center, University of Wisconsin, 1117 West Johnson Street, Madison, Wisconsin 53706, USA. mdjankowski@lanl.gov
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't, Evaluation Studies, Research Support, N.I.H., Extramural