Source:http://linkedlifedata.com/resource/pubmed/id/19182665
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2 Suppl
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pubmed:dateCreated |
2009-2-2
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pubmed:abstractText |
Age-related impairments in wound healing are associated with decreased neovascularization, a process that is regulated by hypoxia-responsive cytokines, including stromal cell-derived factor (SDF)-1 alpha. Interleukin-1 beta is an important inflammatory cytokine involved in wound healing and is believed to regulate SDF-1 alpha expression independent of hypoxia signaling. Thus, the authors examined the relative importance of interleukin (IL)-1 beta and hypoxia-inducible factor (HIF)-1 alpha on SDF-1 alpha expression in aged wound healing.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1529-4242
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
123
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
65S-75S
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pubmed:dateRevised |
2011-2-16
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pubmed:meshHeading |
pubmed-meshheading:19182665-Aging,
pubmed-meshheading:19182665-Animals,
pubmed-meshheading:19182665-Chemokine CXCL12,
pubmed-meshheading:19182665-Disease Models, Animal,
pubmed-meshheading:19182665-Hypoxia-Inducible Factor 1, alpha Subunit,
pubmed-meshheading:19182665-Interleukin-1beta,
pubmed-meshheading:19182665-Mice,
pubmed-meshheading:19182665-Mice, Inbred C57BL,
pubmed-meshheading:19182665-Neovascularization, Physiologic,
pubmed-meshheading:19182665-Wound Healing
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pubmed:year |
2009
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pubmed:articleTitle |
SDF-1 alpha expression during wound healing in the aged is HIF dependent.
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pubmed:affiliation |
Department of Surgery, Division of Plastic Surgery, 257 Campus Drive, GK-201, Stanford, CA 94305-5148, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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