| pubmed-article:19079186 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19079186 | lifeskim:mentions | umls-concept:C0040300 | lld:lifeskim |
| pubmed-article:19079186 | lifeskim:mentions | umls-concept:C0332307 | lld:lifeskim |
| pubmed-article:19079186 | lifeskim:mentions | umls-concept:C0932410 | lld:lifeskim |
| pubmed-article:19079186 | lifeskim:mentions | umls-concept:C0003320 | lld:lifeskim |
| pubmed-article:19079186 | lifeskim:mentions | umls-concept:C0033414 | lld:lifeskim |
| pubmed-article:19079186 | lifeskim:mentions | umls-concept:C1704410 | lld:lifeskim |
| pubmed-article:19079186 | lifeskim:mentions | umls-concept:C0205100 | lld:lifeskim |
| pubmed-article:19079186 | lifeskim:mentions | umls-concept:C1706124 | lld:lifeskim |
| pubmed-article:19079186 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:19079186 | pubmed:dateCreated | 2008-12-16 | lld:pubmed |
| pubmed-article:19079186 | pubmed:abstractText | Multiple mechanisms have evolved to maintain tolerance among CD8(+) T cells to innocuous antigens that arise in cutaneous and mucosal tissues. In the thymus, medullary thymic epithelial cells directly present peripheral tissue antigens (PTAs) and incite the deletion of self-reactive thymocytes. Cross-presentation of PTAs by functionally immature, CD8alpha(+) dendritic cells can lead to the deletion of self-reactive CD8(+) T cells in secondary lymphoid organs. A third mechanism of deletional tolerance has recently been uncovered in which lymph node-resident stromal cells of non-hematopoietic origin present endogenously expressed PTAs to circulating CD8(+) T cells. Emerging data suggest that lymph node stroma is a unique niche for controlling self-reactive T cells. | lld:pubmed |
| pubmed-article:19079186 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19079186 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19079186 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19079186 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19079186 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19079186 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:19079186 | pubmed:issn | 1935-3456 | lld:pubmed |
| pubmed-article:19079186 | pubmed:author | pubmed-author:TurleyS JSJ | lld:pubmed |
| pubmed-article:19079186 | pubmed:author | pubmed-author:LeeJ-WJW | lld:pubmed |
| pubmed-article:19079186 | pubmed:author | pubmed-author:CollierA YAY | lld:pubmed |
| pubmed-article:19079186 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19079186 | pubmed:volume | 1 | lld:pubmed |
| pubmed-article:19079186 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19079186 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19079186 | pubmed:pagination | 248-51 | lld:pubmed |
| pubmed-article:19079186 | pubmed:dateRevised | 2009-5-18 | lld:pubmed |
| pubmed-article:19079186 | pubmed:meshHeading | pubmed-meshheading:19079186... | lld:pubmed |
| pubmed-article:19079186 | pubmed:meshHeading | pubmed-meshheading:19079186... | lld:pubmed |
| pubmed-article:19079186 | pubmed:meshHeading | pubmed-meshheading:19079186... | lld:pubmed |
| pubmed-article:19079186 | pubmed:meshHeading | pubmed-meshheading:19079186... | lld:pubmed |
| pubmed-article:19079186 | pubmed:meshHeading | pubmed-meshheading:19079186... | lld:pubmed |
| pubmed-article:19079186 | pubmed:meshHeading | pubmed-meshheading:19079186... | lld:pubmed |
| pubmed-article:19079186 | pubmed:meshHeading | pubmed-meshheading:19079186... | lld:pubmed |
| pubmed-article:19079186 | pubmed:meshHeading | pubmed-meshheading:19079186... | lld:pubmed |
| pubmed-article:19079186 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:19079186 | pubmed:articleTitle | Self-encounters of the third kind: lymph node stroma promotes tolerance to peripheral tissue antigens. | lld:pubmed |
| pubmed-article:19079186 | pubmed:affiliation | Department of Cancer Immunology and AIDS, Dana Farber Cancer Institute, Boston, Massachusetts, USA. | lld:pubmed |
| pubmed-article:19079186 | pubmed:publicationType | Journal Article | lld:pubmed |
