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rdf:type |
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lifeskim:mentions |
umls-concept:C0032790,
umls-concept:C0242606,
umls-concept:C0301630,
umls-concept:C0392756,
umls-concept:C0567416,
umls-concept:C0752312,
umls-concept:C1258215,
umls-concept:C1370600,
umls-concept:C1415619,
umls-concept:C1527148,
umls-concept:C1709059,
umls-concept:C1710082
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pubmed:issue |
3
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pubmed:dateCreated |
2009-2-12
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pubmed:abstractText |
Treatment with carbon monoxide (CO) inhalation has been shown to ameliorate postoperative ileus (POI) in rodents and swine. The aim of this study was to investigate whether CO liberated from water-soluble CO-releasing molecules (CO-RMs) can protect against POI in mice and to elucidate the mechanisms involved.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1468-3288
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
58
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
347-56
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pubmed:meshHeading |
pubmed-meshheading:19022916-Administration, Inhalation,
pubmed-meshheading:19022916-Animals,
pubmed-meshheading:19022916-Carbon Monoxide,
pubmed-meshheading:19022916-Carboxyhemoglobin,
pubmed-meshheading:19022916-Gastrointestinal Transit,
pubmed-meshheading:19022916-Heme Oxygenase-1,
pubmed-meshheading:19022916-Ileus,
pubmed-meshheading:19022916-Intercellular Adhesion Molecule-1,
pubmed-meshheading:19022916-Intestine, Small,
pubmed-meshheading:19022916-Male,
pubmed-meshheading:19022916-Mice,
pubmed-meshheading:19022916-Mice, Inbred C57BL,
pubmed-meshheading:19022916-Nitric Oxide Synthase Type II,
pubmed-meshheading:19022916-Oxidative Stress,
pubmed-meshheading:19022916-Postoperative Complications,
pubmed-meshheading:19022916-Random Allocation,
pubmed-meshheading:19022916-Signal Transduction
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pubmed:year |
2009
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pubmed:articleTitle |
Water-soluble CO-releasing molecules reduce the development of postoperative ileus via modulation of MAPK/HO-1 signalling and reduction of oxidative stress.
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pubmed:affiliation |
Heymans Institute of Pharmacology, Faculty of Medicine, Ghent University, Ghent, Belgium.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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