|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0005684,
umls-concept:C0007600,
umls-concept:C0017337,
umls-concept:C0055966,
umls-concept:C0079925,
umls-concept:C0086418,
umls-concept:C0279023,
umls-concept:C0334227,
umls-concept:C0599894,
umls-concept:C1515655,
umls-concept:C1533691
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
2009-2-3
|
|
pubmed:abstractText |
To characterize changes in clusterin (sCLU-2) expression in bladder cancer cells after continuous treatment with gemcitabine and to determine whether knockdown of sCLU-2 can re-introduce sensitivity of gemcitabine-resistant cells to treatment with gemcitabine.
|
|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Feb
|
|
pubmed:issn |
1464-410X
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
103
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
384-90
|
|
pubmed:meshHeading |
pubmed-meshheading:19007378-Animals,
pubmed-meshheading:19007378-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:19007378-Blotting, Western,
pubmed-meshheading:19007378-Cell Line, Tumor,
pubmed-meshheading:19007378-Clusterin,
pubmed-meshheading:19007378-Deoxycytidine,
pubmed-meshheading:19007378-Dose-Response Relationship, Drug,
pubmed-meshheading:19007378-Drug Resistance, Neoplasm,
pubmed-meshheading:19007378-Humans,
pubmed-meshheading:19007378-Mice,
pubmed-meshheading:19007378-Mice, Nude,
pubmed-meshheading:19007378-Neoplasm Metastasis,
pubmed-meshheading:19007378-Oligonucleotides, Antisense,
pubmed-meshheading:19007378-Thionucleotides,
pubmed-meshheading:19007378-Urinary Bladder Neoplasms
|
|
pubmed:year |
2009
|
|
pubmed:articleTitle |
Chemosensitization of gemcitabine-resistant human bladder cancer cell line both in vitro and in vivo using antisense oligonucleotide targeting the anti-apoptotic gene, clusterin.
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|
pubmed:affiliation |
The Prostate Centre, Vancouver General Hospital, Vancouver, British Columbia, Canada.
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|
pubmed:publicationType |
Journal Article,
In Vitro
|
