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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2008-11-12
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pubmed:abstractText |
P-glycoprotein (P-gp) mediated classical drug resistance and inhibition of the apoptotic pathway are the two mostly investigated mechanisms of multidrug resistance (MDR). Coexpression and interaction of MDR-related factors result in pleiotropic drug resistance in cancer cells. This study was to investigate the correlation of expressions of multiple MDR-related factors, such as P-gp, p53, Survivin or bcl-2, to chemosensitivitity in gastrointestinal carcinomas.
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pubmed:language |
chi
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1000-467X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1166-71
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:19000447-Adult,
pubmed-meshheading:19000447-Aged,
pubmed-meshheading:19000447-Aged, 80 and over,
pubmed-meshheading:19000447-Antineoplastic Agents,
pubmed-meshheading:19000447-Apoptosis Regulatory Proteins,
pubmed-meshheading:19000447-Colorectal Neoplasms,
pubmed-meshheading:19000447-Drug Resistance, Multiple,
pubmed-meshheading:19000447-Drug Resistance, Neoplasm,
pubmed-meshheading:19000447-Female,
pubmed-meshheading:19000447-Humans,
pubmed-meshheading:19000447-Inhibitor of Apoptosis Proteins,
pubmed-meshheading:19000447-Male,
pubmed-meshheading:19000447-Microtubule-Associated Proteins,
pubmed-meshheading:19000447-Middle Aged,
pubmed-meshheading:19000447-P-Glycoprotein,
pubmed-meshheading:19000447-Proto-Oncogene Proteins c-bcl-2,
pubmed-meshheading:19000447-Stomach Neoplasms,
pubmed-meshheading:19000447-Tumor Suppressor Protein p53,
pubmed-meshheading:19000447-Young Adult
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pubmed:year |
2008
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pubmed:articleTitle |
[Correlation of expression of P-glycoprotein and inhibitor of apoptosis proteins to chemosensitivity in gastrointestinal carcinoma tissues].
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pubmed:affiliation |
Department of Gastrointestinal Surgery, Hebei Provincial People's Hospital, Shijiazhuang, Hebei, China. hanjie01@yahoo.com.cn
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pubmed:publicationType |
Journal Article,
English Abstract,
Research Support, Non-U.S. Gov't
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