Linked Life Data

18985783

Source:http://linkedlifedata.com/resource/pubmed/id/18985783

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2009-9-23
pubmed:abstractText
Molecularly imprinted polymer (MIP) is a technique for generating polymer-bearing biomimetic receptors. It offers several advantages to the research such as analysis, sensors, extraction, or preconcentration of components. Myoglobin is known to be an important biological index for the diagnosis of cardiac diseases. The purpose of this research was to optimize the formation of myoglobin-imprinted polymer (Myo-MIP) and develop a mass spectrometry-based profiling system for assessing the binding selectivity of artificial antibodies formed by Myo-MIP. Experimental results showed that myoglobin and albumin were bound/absorbed onto Myo-MIP chips and not to nonimprinted polymer (NIP) chips. Other proteins, such as histidine-rich glycoprotein, immunoglobulins, proapolipoprotein, and leech-derived tryptase inhibitor, were also observed but with less reproducibility from the chips.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1552-4965
pubmed:author
pubmed:copyrightInfo
(c) 2008 Wiley Periodicals, Inc.
pubmed:issnType
Electronic
pubmed:volume
91
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
597-604
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Assessing the binding selectivity of molecularly imprinted polymer artificial antibodies by mass spectrometry-based profiling system.
pubmed:affiliation
Department of Environmental and Occupational Health, National Cheng Kung University, Tainan, Taiwan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't