Linked Life Data

18955174

Source:http://linkedlifedata.com/resource/pubmed/id/18955174

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2008-10-28
pubmed:abstractText
Current ultrasound methods for measuring myocardial strain are often limited to measurements in one or two dimensions. Cardiac motion and deformation however are truly 3-D. With the introduction of matrix transducer technology, 3-D ultrasound imaging of the heart has become feasible but suffers from low temporal and spatial resolution, making 3-D strain estimation challenging. In this paper, it is shown that automatic intensity-based spatio-temporal elastic registration of currently available 3-D volumetric ultrasound data sets can be used to measure the full 3-D strain tensor. The method was validated using simulated 3-D ultrasound data sets of the left ventricle (LV). Three types of data sets were simulated: a normal and symmetric LV with different heart rates, a more realistic asymmetric normal LV and an infarcted LV. The absolute error in the estimated displacement was between 0.47 +/-0.23 and 1.00 +/-0.59 mm, depending on heart rate and amount of background noise. The absolute error on the estimated strain was 9%-21% for the radial strain and 1%-4% for the longitudinal and circumferential strains. No large differences were found between the different types of data sets. The shape of the strain curves was estimated properly and the position of the infarcts could be identified correctly. Preliminary results on clinical data taken in vivo from three healthy volunteers and one patient with an apical aneurism confirmed these findings in a qualitative manner as the strain curves obtained with the proposed method have an amplitude and shape similar to what could be expected.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1558-0062
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1580-91
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Three-dimensional cardiac strain estimation using spatio-temporal elastic registration of ultrasound images: a feasibility study.
pubmed:affiliation
Department of Electrical Engineering, Medical Image Computing, Katholieke Universiteit Leuven, B-3000 Leuven, Belgium. an.elen@uz.kuleuven.ac.be
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't