Linked Life Data

18950772

Source:http://linkedlifedata.com/resource/pubmed/id/18950772

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
2008-11-10
pubmed:abstractText
Collagens are highly abundant mammalian proteins that contain a high content of hydroxylated amino acids such as hydroxyproline. We have exploited the high hydroxyproline content of collagen and developed a method for hydroxyproline quantification as a measure of collagen content in muscle samples. The novel method utilizes a highly selective and sensitive method of multiple reaction monitoring (MRM) by mass spectrometry. The analytical method is simple, rapid (5min), convenient (no derivatization), precise (<17% RSD), accurate (90-108%), sensitive (4.88nmol/L) and linear (R(2)>0.999) over three orders of magnitude (5-5000nmol/L).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0021-9673
pubmed:author
pubmed:issnType
Print
pubmed:day
28
pubmed:volume
1212
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
150-3
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Hydroxyproline quantification for the estimation of collagen in tissue using multiple reaction monitoring mass spectrometry.
pubmed:affiliation
Queensland Bioscience Precinct, St Lucia, QLD 4067, Australia. michelle.colgrave@csiro.au
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Evaluation Studies