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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2008-9-8
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pubmed:abstractText |
Moderate alcohol consumption appears to confer some protection against coronary heart disease, which is related to an increase in high-density lipoprotein cholesterol (HDL-C). The genotype of aldehyde dehydrogenase 2 (ALDH2) is closely related to alcohol metabolism but a relationship between ALDH2 genotypes and HDL-C levels has not been proven. We undertook a large-scale correlation study between HDL-C levels and ALDH2 genotype among Japanese non-drinkers to investigate the possibility that HDL-C levels could be associated with ALDH2 genotype.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1880-3873
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pubmed:author |
pubmed-author:DaimonMakotoM,
pubmed-author:EmiMitsuruM,
pubmed-author:HopkinsPaul NPN,
pubmed-author:HuntSteven CSC,
pubmed-author:IijimaHiroshiH,
pubmed-author:KatoTakeoT,
pubmed-author:KawanamiToruT,
pubmed-author:KawataSumioS,
pubmed-author:KoyanoSatoruS,
pubmed-author:KubotaIsaoI,
pubmed-author:KuritaKeijiK,
pubmed-author:SatoHidenoriH,
pubmed-author:TajimaKatsushiK,
pubmed-author:WadaManabuM
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pubmed:issnType |
Electronic
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
179-84
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pubmed:meshHeading |
pubmed-meshheading:18776700-Aged,
pubmed-meshheading:18776700-Alcohol Drinking,
pubmed-meshheading:18776700-Aldehyde Dehydrogenase,
pubmed-meshheading:18776700-Cholesterol, LDL,
pubmed-meshheading:18776700-Female,
pubmed-meshheading:18776700-Genotype,
pubmed-meshheading:18776700-Humans,
pubmed-meshheading:18776700-Japan,
pubmed-meshheading:18776700-Male,
pubmed-meshheading:18776700-Middle Aged,
pubmed-meshheading:18776700-Polymorphism, Single Nucleotide,
pubmed-meshheading:18776700-Population Surveillance
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pubmed:year |
2008
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pubmed:articleTitle |
Genetic association between aldehyde dehydrogenase 2 (ALDH2) variation and high-density lipoprotein cholesterol (HDL-C) among non-drinkers in two large population samples in Japan.
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pubmed:affiliation |
Department of Neurology, Faculty of Medicine, Yamagata University, Japan. mwada@yacht.ocn.ne.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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