Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2 Suppl
pubmed:dateCreated
2008-8-19
pubmed:abstractText
Folate deficiency in the periconceptional period contributes to neural tube defects; deficits in vitamin B12 (cobalamin) have negative consequences on the developing brain during infancy; and deficits of both vitamins are associated with a greater risk of depression during adulthood. This review examines two mechanisms linking folate and vitamin B12 deficiency to abnormal behavior and development in infants: disruptions to myelination and inflammatory processes. Future investigations should focus on the relationship between the timing of deficient and marginal vitamin B12 status and outcomes such as infant growth, cognition, social development, and depressive symptoms, along with prevention of folate and vitamin B12 deficiency.
pubmed:grant
pubmed:commentsCorrections
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pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0379-5721
pubmed:author
pubmed:issnType
Print
pubmed:volume
29
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S126-31
pubmed:dateRevised
2011-9-26
pubmed:meshHeading
pubmed-meshheading:18709887-Humans, pubmed-meshheading:18709887-Pregnancy, pubmed-meshheading:18709887-Depression, pubmed-meshheading:18709887-Adolescent, pubmed-meshheading:18709887-Infant, pubmed-meshheading:18709887-Brain, pubmed-meshheading:18709887-Aged, pubmed-meshheading:18709887-Child, pubmed-meshheading:18709887-Infant, Newborn, pubmed-meshheading:18709887-Folic Acid, pubmed-meshheading:18709887-Child, Preschool, pubmed-meshheading:18709887-Female, pubmed-meshheading:18709887-Male, pubmed-meshheading:18709887-Vitamin B 12, pubmed-meshheading:18709887-Adult, pubmed-meshheading:18709887-Folic Acid Deficiency, pubmed-meshheading:18709887-Vitamin B 12 Deficiency, pubmed-meshheading:18709887-Middle Aged, pubmed-meshheading:18709887-Prenatal Exposure Delayed Effects, pubmed-meshheading:18709887-Nutritional Status
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