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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2008-12-29
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pubmed:abstractText |
Urokinase-type plasminogen activator (uPA) and urokinase-type plasminogen activator receptor (uPAR) are known to be important factors in the pathogenesis of tumors and certain non-viral inflammatory diseases. However, their role in infectious virus diseases such as hepatitis B has been less well studied. This study aimed to test the hypothesis that the abnormalities of fibrinolysis and degradation of extracellular matrix mediated by uPA and uPAR are directly related to the inflammatory damage to liver cells caused by the hepatitis B virus. We therefore analyzed their role and clinicopathological significance in patients with acute or chronic hepatitis B.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0049-3848
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
123
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
537-42
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pubmed:meshHeading |
pubmed-meshheading:18691743-Acute Disease,
pubmed-meshheading:18691743-Adult,
pubmed-meshheading:18691743-Aged,
pubmed-meshheading:18691743-Bilirubin,
pubmed-meshheading:18691743-Biological Markers,
pubmed-meshheading:18691743-Case-Control Studies,
pubmed-meshheading:18691743-Female,
pubmed-meshheading:18691743-Hepatitis B,
pubmed-meshheading:18691743-Hepatitis B, Chronic,
pubmed-meshheading:18691743-Humans,
pubmed-meshheading:18691743-Inflammation,
pubmed-meshheading:18691743-Male,
pubmed-meshheading:18691743-Middle Aged,
pubmed-meshheading:18691743-Prognosis,
pubmed-meshheading:18691743-Prothrombin Time,
pubmed-meshheading:18691743-Receptors, Urokinase Plasminogen Activator,
pubmed-meshheading:18691743-Risk Factors,
pubmed-meshheading:18691743-Urokinase-Type Plasminogen Activator,
pubmed-meshheading:18691743-Young Adult
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pubmed:year |
2009
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pubmed:articleTitle |
Evaluation of plasma urokinase-type plasminogen activator and urokinase-type plasminogen-activator receptor in patients with acute and chronic hepatitis B.
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pubmed:affiliation |
Department of Clinical Laboratory, Zhejiang Hospital, Hangzhou 310013, China.
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pubmed:publicationType |
Journal Article
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