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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2008-12-16
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pubmed:abstractText |
Pretreatment with cyclosporine, a P-glycoprotein (P-gp) modulator increases brain uptake of 4-(2'-methoxyphenyl)-1-[2'-(N-2"-pyridinyl)-p-[(18)F]fluorobenzamido]ethylpiperazine ([(18)F]MPPF) for binding to hydroxytryptamine(1A) (5-HT(1A)) receptors. Those increases were quantified in rat brain with in vivo microPET and ex vivo tissue studies.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1619-7089
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
35
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2256-66
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pubmed:meshHeading |
pubmed-meshheading:18604533-Animals,
pubmed-meshheading:18604533-Brain,
pubmed-meshheading:18604533-Corpus Striatum,
pubmed-meshheading:18604533-Cyclosporine,
pubmed-meshheading:18604533-Hippocampus,
pubmed-meshheading:18604533-Male,
pubmed-meshheading:18604533-P-Glycoprotein,
pubmed-meshheading:18604533-Piperazines,
pubmed-meshheading:18604533-Positron-Emission Tomography,
pubmed-meshheading:18604533-Pyridines,
pubmed-meshheading:18604533-Rats,
pubmed-meshheading:18604533-Receptor, Serotonin, 5-HT1A,
pubmed-meshheading:18604533-Tissue Distribution
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pubmed:year |
2008
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pubmed:articleTitle |
Cyclosporine, a P-glycoprotein modulator, increases [18F]MPPF uptake in rat brain and peripheral tissues: microPET and ex vivo studies.
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pubmed:affiliation |
Department of Molecular and Medical Pharmacology, UCLA, Los Angeles, CA 90095-1735, USA.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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