rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
2008-7-2
|
pubmed:abstractText |
Cytokine-induced killer cells (CIKs) are nonspecific antitumor effectors with superior advantages. CD4+ CIKs can induce Fas-dependent apoptosis in sensitive Raji cells. Here, a Fas-dependent apoptosis was detected in resistant breast cancer MDA-MB-231 cells, and underlying mechanisms were discriminated.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
1557-8852
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
23
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
342-54
|
pubmed:dateRevised |
2010-9-16
|
pubmed:meshHeading |
pubmed-meshheading:18593367-Aged,
pubmed-meshheading:18593367-Antigens, CD95,
pubmed-meshheading:18593367-Apoptosis,
pubmed-meshheading:18593367-Breast Neoplasms,
pubmed-meshheading:18593367-CASP8 and FADD-Like Apoptosis Regulating Protein,
pubmed-meshheading:18593367-CD4-Positive T-Lymphocytes,
pubmed-meshheading:18593367-CD40 Ligand,
pubmed-meshheading:18593367-Cell Line, Tumor,
pubmed-meshheading:18593367-Drug Resistance,
pubmed-meshheading:18593367-Female,
pubmed-meshheading:18593367-Humans,
pubmed-meshheading:18593367-Interferon-gamma,
pubmed-meshheading:18593367-Male,
pubmed-meshheading:18593367-Middle Aged,
pubmed-meshheading:18593367-Protein Structure, Tertiary
|
pubmed:year |
2008
|
pubmed:articleTitle |
CD4+T cells in CIKs (CD4+ CIKs) reversed resistance to fas-mediated apoptosis through CD40/CD40L ligation rather than IFN-gamma stimulation.
|
pubmed:affiliation |
Department of Immunology, Tianjin Cancer Institute & Hospital of Tianjin Medical University, Tianjin, China.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|