Source:http://linkedlifedata.com/resource/pubmed/id/18555770
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2008-6-16
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pubmed:abstractText |
Dominantly inherited mutations in an endoplasmic reticulum protein called VAPB have been found in a subset of patients with a rare familial form of amyotrophic lateral sclerosis (ALS). In this issue, Tsuda et al. (2008) identify a secreted form of VAPB that binds directly to Eph receptors inducing their activation and signaling, providing fresh insights into ALS pathogenesis, including non-neuronal aspects of this disorder.
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pubmed:grant | |
pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1097-4172
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
13
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pubmed:volume |
133
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
949-51
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading | |
pubmed:year |
2008
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pubmed:articleTitle |
From ER to Eph receptors: new roles for VAP fragments.
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pubmed:affiliation |
The Jackson Laboratory, Bar Harbor, ME 04609, USA. susan.ackerman@jax.org
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pubmed:publicationType |
Journal Article,
Comment,
Research Support, Non-U.S. Gov't
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