Source:http://linkedlifedata.com/resource/pubmed/id/18456428
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2009-4-27
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pubmed:abstractText |
MRSA-carrier screening is recommended to prevent MRSA dissemination in hospitals. Rapid and specific detection of MRSA in the laboratory is a key element in enabling control measures. Our objective was to evaluate the impact of different lengths of pre-incubation in a nutritive broth and prolonged incubation of MRSA-ID, a chromogenic agar medium, on its performances for identifying MRSA in screening samples. According to our results, short-length pre-enrichments only provided a weak increase of sensitivity as compared to the absence of pre-enrichment. On the contrary, the sensitivity increase provided by an overnight pre-enrichment was significant. The prolongation of incubation in the chromogenic agar medium (48 hours instead of 24 hours) did not provide any significant increase of sensitivity but was associated with a strong and significant loss of specificity. Therefore, it seems relevant to reject prolonged incubation of selective agar media and to make a choice between the absence of pre-enrichment (faster results) and an overnight pre-enrichment (higher sensitivity), according to local epidemiology and local practices implemented for prevention.
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pubmed:language |
fre
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1768-3114
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
57
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e37-42
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pubmed:meshHeading |
pubmed-meshheading:18456428-Agar,
pubmed-meshheading:18456428-Carrier State,
pubmed-meshheading:18456428-Culture Media,
pubmed-meshheading:18456428-Hospitals,
pubmed-meshheading:18456428-Humans,
pubmed-meshheading:18456428-Inpatients,
pubmed-meshheading:18456428-Kinetics,
pubmed-meshheading:18456428-Mass Screening,
pubmed-meshheading:18456428-Methicillin-Resistant Staphylococcus aureus,
pubmed-meshheading:18456428-Sensitivity and Specificity,
pubmed-meshheading:18456428-Staphylococcal Infections,
pubmed-meshheading:18456428-Time Factors
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pubmed:year |
2009
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pubmed:articleTitle |
[Evaluation of the impact of different lengths of pre-enrichment in a nutritive broth and prolonged incubation of MRSA-ID, a chromogenic agar medium, on its performances for identifying methicillin-resistant Staphylococcus aureus in screening samples].
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pubmed:affiliation |
Service de Microbiologie-Hygiène, Hôpital Louis-Mourier (AP-HP), 178 Rue des Renouillers, 92700 Colombes, France.
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pubmed:publicationType |
Journal Article,
English Abstract
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