1844684

Source:http://linkedlifedata.com/resource/pubmed/id/1844684

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0205092, umls-concept:C0332147, umls-concept:C0598333, umls-concept:C1442065, umls-concept:C1709380
pubmed:issue	1
pubmed:dateCreated	1993-5-27
pubmed:abstractText	Whether a one-sided or a two-sided p value should be used for reporting the results of an analysis should be determined by the a priori question the investigation seeks to answer. It is concluded that one-sided p values are appropriate in clinical trials whose objective is to provide definitive, confirmatory evidence of efficacy of pharmaceutical compounds.
pubmed:commentsCorrections	http://linkedlifedata.com/resource/pubmed/commentcorrection/1844684-8732915
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9200436
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:issn	1054-3406
pubmed:author	pubmed-author:PeaceK EKE
pubmed:issnType	Print
pubmed:volume	1
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	133-8
pubmed:dateRevised	2007-11-15
pubmed:meshHeading	pubmed-meshheading:1844684-Biopharmaceutics, pubmed-meshheading:1844684-Clinical Trials as Topic, pubmed-meshheading:1844684-Humans, pubmed-meshheading:1844684-Research Design
pubmed:year	1991
pubmed:articleTitle	One-sided or two-sided p values: which most appropriately address the question of drug efficacy?
pubmed:affiliation	Biopharmaceutical Research Consultants, Inc., Ann Arbor, Michigan 48105.
pubmed:publicationType	Journal Article, Review