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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2008-5-22
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pubmed:abstractText |
Atherosclerosis is a chronic inflammatory disease that represents the primary cause of death through coronary disease and stroke. Chemokines are known to play a crucial role in this disease by recruiting inflammatory leukocytes to the endothelium. Recently, the chemokine variant [44AANA47]-RANTES was shown to impair inflammatory cell recruitment in vivo by interfering with heparin binding and oligomerization.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Ccr2 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CCL2,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CCL5,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokines,
http://linkedlifedata.com/resource/pubmed/chemical/Collagen,
http://linkedlifedata.com/resource/pubmed/chemical/Heparin,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 9,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, CCR2,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, CCR5,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, LDL
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1524-4636
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1090-6
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pubmed:meshHeading |
pubmed-meshheading:18388327-Animals,
pubmed-meshheading:18388327-Aorta,
pubmed-meshheading:18388327-Atherosclerosis,
pubmed-meshheading:18388327-Chemokine CCL2,
pubmed-meshheading:18388327-Chemokine CCL5,
pubmed-meshheading:18388327-Chemokines,
pubmed-meshheading:18388327-Collagen,
pubmed-meshheading:18388327-Disease Models, Animal,
pubmed-meshheading:18388327-Disease Progression,
pubmed-meshheading:18388327-Heparin,
pubmed-meshheading:18388327-Leukocytes,
pubmed-meshheading:18388327-Male,
pubmed-meshheading:18388327-Matrix Metalloproteinase 9,
pubmed-meshheading:18388327-Mice,
pubmed-meshheading:18388327-Mice, Inbred C57BL,
pubmed-meshheading:18388327-Mice, Transgenic,
pubmed-meshheading:18388327-Receptors, CCR2,
pubmed-meshheading:18388327-Receptors, CCR5,
pubmed-meshheading:18388327-Receptors, LDL
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pubmed:year |
2008
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pubmed:articleTitle |
A novel RANTES antagonist prevents progression of established atherosclerotic lesions in mice.
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pubmed:affiliation |
Division of Cardiology, Department of Medicine, University Hospital, Foundation for Medical Researches, 64 Avenue Roseraie, 1211 Geneva, Switzerland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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