|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0004083,
umls-concept:C0007137,
umls-concept:C0013081,
umls-concept:C0017262,
umls-concept:C0027651,
umls-concept:C0042172,
umls-concept:C0042666,
umls-concept:C0185117,
umls-concept:C0460004,
umls-concept:C0580822,
umls-concept:C1523298,
umls-concept:C1547300,
umls-concept:C1548760,
umls-concept:C1550594,
umls-concept:C1879547,
umls-concept:C2348519,
umls-concept:C2911684
|
|
pubmed:issue |
9
|
|
pubmed:dateCreated |
2008-4-28
|
|
pubmed:abstractText |
Epithelial-mesenchymal transformations (EMT) are critical for the invasion, progression, and metastasis of epithelial carcinogenesis. The role of EMT in head and neck squamous carcinoma (HNSC) tumorigenesis remains unexplored. In the current study, the expressions of several factors associated with the induction of EMT in HNSC cell lines and tumor specimens were investigated to define their functional and pathologic role in HNSC.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
0008-543X
|
|
pubmed:author |
pubmed-author:El-NaggarAdel KAK,
pubmed-author:GallickGary EGE,
pubmed-author:JohnsonFaye MFM,
pubmed-author:LippmanScott MSM,
pubmed-author:MandalMahitoshM,
pubmed-author:MyersJeffery NJN,
pubmed-author:OhshiroKazufumiK,
pubmed-author:RayalaSureshS,
pubmed-author:RosenthalDavid IDI,
pubmed-author:WeberRandal SRS,
pubmed-author:WilliamsMichelle DMD
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
1
|
|
pubmed:volume |
112
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
2088-100
|
|
pubmed:dateRevised |
2009-11-19
|
|
pubmed:meshHeading |
pubmed-meshheading:18327819-Cadherins,
pubmed-meshheading:18327819-Carcinoma, Squamous Cell,
pubmed-meshheading:18327819-Cell Line, Tumor,
pubmed-meshheading:18327819-Cell Proliferation,
pubmed-meshheading:18327819-Down-Regulation,
pubmed-meshheading:18327819-Enzyme Activation,
pubmed-meshheading:18327819-Epithelium,
pubmed-meshheading:18327819-Head and Neck Neoplasms,
pubmed-meshheading:18327819-Humans,
pubmed-meshheading:18327819-Immunohistochemistry,
pubmed-meshheading:18327819-Mesoderm,
pubmed-meshheading:18327819-Pyrimidines,
pubmed-meshheading:18327819-RNA, Small Interfering,
pubmed-meshheading:18327819-Receptor, Epidermal Growth Factor,
pubmed-meshheading:18327819-src-Family Kinases
|
|
pubmed:year |
2008
|
|
pubmed:articleTitle |
Epithelial to mesenchymal transition in head and neck squamous carcinoma: association of Src activation with E-cadherin down-regulation, vimentin expression, and aggressive tumor features.
|
|
pubmed:affiliation |
Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|
